Has anyone here taken navelbine or had a loved one who did and had a bowel shut down? We are caregivers for a relative who had his first navelbine on August 27th, had mouth sores and throat sores by August 29th-31, stopped moving his bowels by the 30th, and was hospitalized when he started vomiting blood on Sept 2nd. The doctors said "his intestines are not doing anything" and assumed a small bowel obstruction. Upon further examamination, they couldn't find any reason for an obstruction, and just kept suctioning out his stomach. Now, in the last day, his bowels have started to function a little and he is moving some waste out with enemas.
My question is: If the doctor suggests a lesser dose of Navelbine, which was determined to be the most effective for his tumors in a study they did on them specifically in a lab in California, should we consider it? This hospitalization has been very hellish and frightening.
He is 4th stage NSCLC, diagnosed in April 2006, and previously had 12 weeks of Taxotere & Carboplatin (reduced the nodes a lot), then 12 weeks of Tarceva (did nothing), then to Alimta, which did not reduce the nodes, but stopped the cancer activity, then one treatment of Gemzar (end of March) which sent him into seizures and he refused further treatment, then in June began having large tumors appearing in his neck and under his arm again. Radiation was done on the axilliary to good effect (got rid of the pain), and then radiation was done on his neck (gave him back his voice 80%).
Any suggestions to those who have been there done that? He's a real fighter with the best attitude anyone could believe, never complaining, always upbeat.