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please help

crm22
Posts: 1
Joined: Jul 2007

My uncle who is like my faather is in what we think are the final stages of liver cancer. the doctors have given up but he hasn't. what are some signs and treatments that we can try. Please help. he has two young children and a huge family who loves him dearly. somone please let me know some of the signs of the final stages.

annes449's picture
annes449
Posts: 15
Joined: Jun 2005

You don't say what kind of liver cancer you are dealing with. I lost my significant other to hepatocellular carcinoma.

I think the most significant symtom was his complete lose of interest in food or drink. It wasn't very long after he lost his appetite that we lost him.

Be kind to each other. The kindness we shared at the end of my significant others life has stayed with me since I lost him and continues to be important to me.

Take every opportunity to say I love you. Hold his hand. Watch a favorite movie. Play a favorite game if he feels like it.

As I type this I remember out last game of scrabble. We actually watched his favorite series from start to finish and it helped us to enjoy our time together. He didn't feel like doing much, but, we could hold hands and watch a show.

Do what you can and live.

Peace,
Anne

Delcath1
Posts: 2
Joined: Jul 2007

There are a number of treatments available, many of which are in clinical trial phase. A medical device company has been testing a drug delivery platform for the targeted delivery of ultra-high doses of chemotherapeutic drugs while protecting patients from the harmful side effects of chemotherapy. Doctors at the National Cancer Institute use catheters placed percutaneously in a process called percutaneous hepatic perfusion. Having produced dramatic responses in Phase I clinical trials, the testing leaped to the pivotal Phase III trial, currently underway. The treatment is currently being used for a variety of tumors in the liver, but can be adapted to isolate other organs and body regions, as demonstrated in animal trials. By isolating an organ, the device, from Delcath Systems, allows for the targeted delivery of chemotherapeutic agents in much higher doses, thereby improving therapeutic benefit while minimizing systemic toxicity. The Phase III trial currently underway at the NCI is delivering several times the FDA approved dosage of melphalan for the treatment of metastatic melanoma in the liver. The NCI is also currently enrolling patients in a Phase II trial with the system, for primary liver cancer and metastatic hepatic malignancies from neuroendocrine cancers and adenocarcinomas, as well as for patients with melanoma.

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