May 06, 2004 - 3:35 pm
My niece just began her first round of methotrexate in her second round of chemotherapy. Each round begins with cisplatin, two weeks off, and then two weeks of high dose methotrexate. The oncologist is very concerned as her creatning levels are way too high and the methotrexate does not seem to be leaving her system well enough. They are talking about discontinuing the methotrexate altogether. Has anyone ever experienced this and what was done? Thanks!