Mar 03, 2004 - 1:55 pm
I am a 55 year-old African American male diagnosed with PCa in Feburary of 2002. My PCP refered me to a urologist in December of 2001 based on the doubling of my 2000 PSA level(from 2 to 4). I underwent a radical RPP at Johns Hopkins in May of 2002 (PSA of 6.5). Post-op pathology indicated microscopic pelvic lymph node involvement (2 out of 6 sampled). I participated in an adjuvant Taxotere clinical trial at JHH for 6 months (June-December 2002). My post chemo PSA (Jan 2003) was .5. From January 2003 to January 2004 my PSA level had a doubling rate of 6 months to 13.5. Last month, a bone scan indicated pelvic abnormalities and an MRI confired the presence of bone metastasis, single location. I started hormone therapy last month. There is no history of PCa in my family and I have been taking PSA tests since the late 1980's. My oncologist, Dr. Mario Eisenberger, said that he believes that the boney metastasis was present (but not detectable) at the time of my RPP, thus at a PSA level of 4.0. Is my case unusual? That is to say, how often does one find such advanced involvement at so low a PSA level?