Metformin as anti-cancer agent

AussieMaddie said:

Hi all
thouht I'd add my
Hi all

thouht I'd add my experience to the mix. Don't know that it will enlighten at all though. I was started on Metformin years ago not because I was diabetic but because I was considered to be pre-diabetic (glucose impaired?) because I was so big. My BMI was probably about 50. Since then, I lost 42kg on the weight loss drug Reductil (*everything* went down, including my blood sugar - no longer pre-diabetic, but not taken off the Metformin). Reductil blamed by one doctor for my needing a pacemaker a few months after it stopped working. In that time, I started putting back on all the weight. Up 32kg when I thought my distended stomach felt different, not going down in between food binges. So did my doctor. The next week, thinking "Nope, something *is* different" I saw a different doctor, who sent me for an ultrasound. "10kg fluid in abdomen". *That's* why it wasn't going down. Into hospital. Ascites. Cancer of the peritoneaum, but primary considered to be elsewhere, just "unknown". Drained of fluid, lost more weight in hospital (couldn't binge) and down to my lowest of 85kg. Started on chemo, not sick from that so bingeing started up again in earnest - high in sugar and particularly fats, the whole time still on Metformin. Still am. And now I'm getting closer to the weight I had before the Reductil. CT scans at start of chemo showed no sign at all of any kind of tumour. Only the fluid (ascites) was seen to carry the cancer. A PET scan taken a couple of months ago approx. surprisingly also showed abosolutely nothing.

Might the Metformin have anything to do with my complete lack of the evidence of tumours?

The CA125 has been slowly climbing since before I finished the chemo about two months ago. Onc. says it because it has stopped being effective. Wating to see how it goes at present. Still no symptoms yet (except possibly for a twinge one or twice in the left pelvic area over the past month)

Am kept on Metformin only because of my size and my bingeing, but more often than not I forget to take the 2nd one.

Don't know that it has helped cause a lack of symptoms from the cancer or not. But if diet is a cause, then I should be long gone!

AussieMaddie

excersise
I may be finally able to go back to the YMCA and resumes my water aroebics class and maybe zumba. My Dr gave me some lidocaine cream to rub on my feet. I tried some at work the other night and It helped me make it through the rest of my shift. I am hoping to get my A1C back down to 6,,,,,,wish me luck...val