Good News!

CheeseQueen57
CheeseQueen57 Member Posts: 933 Member

Just saw my oncologist. The Megace is holding the beast off!  Glory be to God!  Now I just have some hydroureronephrosis of my right kidney. I was just at urologist a couple months ago!  It’s always something. But for now, I’m happy. Just need to get rid of migraines. 

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Comments

  • oldbeauty
    oldbeauty Member Posts: 319 Member
    Wonderful news!

    So happy the progesterone is working for you.  What is your monitoring protocol, if I may ask? Best wishes, Oldbeauty

  • evolo58
    evolo58 Member Posts: 293
    Happy dance here! That is

    Happy dance here! That is GREAT news. Congrats!

     

  • CheeseQueen57
    CheeseQueen57 Member Posts: 933 Member
    oldbeauty said:

    Wonderful news!

    So happy the progesterone is working for you.  What is your monitoring protocol, if I may ask? Best wishes, Oldbeauty

    Monitoring

    At this point I get labs and CT scan every 3 months. I’m concerned about so frequent CT scans but I’ve never had more than 8 months of stability so at this point it is what it is. CA 125 never has been any value to me. 

  • TeddyandBears_Mom
    TeddyandBears_Mom Member Posts: 1,811 Member
    Great news, Cheese! So happy

    Great news, Cheese! So happy for you. Here's to keeping that kind of news coming!

    Love and Hugs,

    Cindi

  • ConnieSW
    ConnieSW Member Posts: 1,613 Member
    Good news

     You have had so much to deal with, one thing after another. It's way past time for a break. Let's hope you're on a roll. 

  • SF73
    SF73 Member Posts: 316 Member
    Three cheers for Megace!

    So happy to hear it is working for you. May I ask if you know the receptor levels of your tumor? I am also on Megace since October (160 mg / day) and just found out that the results from the second pathology report that only 25% of the cells are PR receptive and 50% of the cells are ER receptive. I was a bit disappointed with that since my cancer is of type 1, endometrioid histology, it is usually thought to be hormonally driven and the numbers suggest it is only moderately so. According to the papers below it seems cancer that is PR positive is more likely to respond to hormone therapy.

    For those of you who might be interested in reading a bit more about use of hormone therapy in advanced and recurrent endometrial cancer, these two papers are interesting:

    https://www.sciencedirect.com/science/article/pii/S1726490114000483

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014387/

  • MAbound
    MAbound Member Posts: 1,164 Member
    Congrats!

    Hey Cheese! That's just what we all needed to hear! That's the important mole to whack! Now if you can just get the other ones ;-)! Keep at it girl! It's a drag, but it's our reality.

    SF73...are you taking Metformin? It can help reactivate PR sensitivity, so it's very helpful to take when on Megace therapy.

  • SF73
    SF73 Member Posts: 316 Member
    Metformin

    Hi MABound,

    I am on Metformin (850 mg x 2 / day) and was encouraged to see the articles you have shared which discussed Metformin's ability to increase PR sensitivity. I just thought due to the histology of my tumor PR sensitivity would already be high and that I wouldn't need the boost from Metformin but I guess that is not always true. I do not mind being on these two drugs for the rest of my life if it means we can keep cancer at bay. Thanks for your note. 

  • CheeseQueen57
    CheeseQueen57 Member Posts: 933 Member
    edited January 2018 #10

    Gee, I don’t know my PR receptor levels. There’s just so much to know!!  i  too am taking 160mg day (afraid it’s having something to do with my migraines. Hmmm migraines vs cancer. ). Anyway we were not too optimistic about the Megace because although my tumor was hormone receptive my tumor was high grade and I am over 60. So I was pleasantly surprised. Although my oncologist flatly refuses to prescribe metformin I’m really working over my endocrinologist to prescribe it. Hopefully I will be successful if I can solve this kidney issue. I hope the Megace works for you too. 

  • MAbound
    MAbound Member Posts: 1,164 Member
    Triggers

    You may not be able to do much about hormonal changes making you susceptible to migraines now, (like you said: cancer vs migrains) but trying to identify your triggers can go a long way towards having them less often. It takes time to figure them out, but it's worth keeping a log of circumstances to track them down. You're probably sensitive to stuff now that never bothered you before. Not fun!

  • NoTimeForCancer
    NoTimeForCancer Member Posts: 3,032 Member
    edited January 2018 #12
    Great news!!!!  

    Great news!!!!  

  • CheeseQueen57
    CheeseQueen57 Member Posts: 933 Member
    Triggers

    I’ve had migraines my entire life. They pretty much stopped when I got past menopause. Yippee. But the auras came back with chemo. But after the stroke I didn’t have any. Until now. I thought it was because I started drinking a lot of tea and ate a bunch of chocolate. But triggers can be stress, barometric pressure ( who can avoid those), cheese, onions, medicines everything in your environment. When my dad died- no migraines. I got let go from a job I’d had 10 years- no migraines. I ate a bunch of chocolate- no migraines. My PCP said the triggers can be cumulative. Great. I’ve given up on trying to avoid triggers It would drive me nuts and make my already sucky quality of life worse. I’ll take my chances with triggers and hopefully get this under control with some good meds. What’s a few more?

  • EZLiving66
    EZLiving66 Member Posts: 1,476 Member
    I'm so glad to hear the good

    I'm so glad to hear the good news!! May it continue for many,  many years.

    Love, 

    Eldri 

  • JinVa
    JinVa Member Posts: 29
    CheeseQueen - great news!

    thanks so much for sharing and may you continue to have good results. Here's to a healthier and happy 2018!

  • Jairoldi
    Jairoldi Member Posts: 221
    edited January 2018 #16
    Terrific!

    That is terrific news!

  • MrsBerry
    MrsBerry Member Posts: 102
    Yay! I am so happy for you,

    Yay! I am so happy for you, CheeseQueen! 

  • derMaus
    derMaus Member Posts: 558
    Yay, Cheese!

    This is the best news! Thank you for sharing it with us. I'm SO GLAD this treatment is working out for you. Blessed be, indeed ! B

  • takingcontrol58
    takingcontrol58 Member Posts: 264 Member
    Cheese Queen, good news

    Glad to hear the Megace is keeping you stable.

    Keep working on your endocrinologist to get on the metformin. Persistence pays off.

     

    Takingcontrol58

  • HorseLvr
    HorseLvr Member Posts: 102
    That is great news,

    That is great news, CheeseQueen!

  • MoeKay
    MoeKay Member Posts: 403 Member
    Wonderful News

    Sounds like 2018 is going to be your year, Cheese!  Congratulations on the wonderful news you received from your oncologist on the Megace!!  I hope you also get the migraines and kidney issue resolved in the very near future.  You know, headaches can be a real mystery.  I used to get bad headaches on a regular basis for many years until my cancer diagnosis and treatment.  In the eighteen years since then, I have not had a headache.  I'm assuming hormones must have played a big role in my case.  So when people ask me what I did to treat my headaches, I told them I got cancer!!

    All the best,

    MoeKay