Mar 26, 2014 - 12:42 pm
Went to the doctor and my marker went from 705 to 905. He gave me several options. When I came to Florida my marker was 712 from September so to raise only 200 points in 6 months is a slower rise, for me Than previously.
1) have a CAT scan and if it shows significant increase in lymph nodes, go back on Taxol/cisplatin.
2). Have a CAT scan and start Doxil if treatment needed at this time. I told him I dreaded the side effects of Doxil. He said some people do well with it, but others could only take 2 doses because of the side effects. You don't know until you try it, how you will react and if it works.
3) try a new aromatase inhibitor - Letrozole, to see if it slows the cancer growth better. He also mentioned tamoxifen , but it increases the risk of blood clots, since I have had multiple blood clots in both lungs that is not an option for me. I tried Arimidex before, and it did not work for me, so I am hesitant to try something different.
4) enter a clinical trial. It is a phase 2 trial. It is with Adriamycin or an isomer of Adriamycin. You do not know which drug you will get. To be part of the clinical trial we would need to stay in Florida, and since we are going back to Illinois for the summer, I can not enter the trial. He was not sure I would meet all the criteria to enter the trial. He would need to check. He says that Adriamycin has proven useful in treating in Uterine cancer, but I have not seen anyone on this board who has taken it. Maybe because it is still in clinical trials.
in checking the Internet it looks like Adriamycin is in the same family as Doxil, but a much older drug. Much like carboplatin and cisplatin are in the platinum drug family.
5) continue the same as I am doing with the Aromasin and repeat the CA 125 in 2 months.
I asked if I chose the Doxil and it did not work, could I go back to the taxol/ cisplatin since that did work. He said yes, I was not closing any doors. I chose option 5. It has been 22 months since my last chemo. My marker went up to 1700 after 18 months when I had chemo the second time. And it went up to 3200 after 7 months when I had chemo the third time.
I am going for quality of life. The longer i can be off chemo the better for my body. The doctor is okay with me continuing the same Medication and observation. He said by waiting it would not effect the usefulness of the treatment in the future. I have a follow up appointment in Illinois in May.
I also asked him if I was diagnosed today with UPSC 3-C would he still recommend the sandwich treatment for me. I told him about someone else who went to Moffitt, where I go, that had all chemo then radiation. He said yes he would recommend the sandwich treatment. He said that some thoughts are that if you have all the chemo first then the body has a harder time with the radiation. So different doctors have different theories.
i am still symptom free, so I will continue to give thanks for each day, and enjoy each Day. Hope you are all doing well. In peace and caring.