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robinleigh's picture
Posts: 297
Joined: Mar 2011

So where does this cancer usually metastasize? It's not bone because I can't find anyone herevwith bone mets.

Hondo's picture
Posts: 6643
Joined: Apr 2009

Squamous cell carcinoma (SCC or SqCC), occasionally rendered as "squamous-cell carcinoma", is a histologically distinct form of cancer. It arises from the uncontrolled multiplication of malignant cells deriving from epithelium, or showing particular cytological or tissue architectural characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, and/or desmosomes).

Squamous cell carcinoma is one of the most common cancers in humans and other animals, and usually arises from mutated ectodermal or endodermal cells lining body cavities. Therefore, it can develop in a large number of organs and tissues, including the skin, lips, mouth, esophagus, urinary bladder, prostate, lung, vagina, and cervix, among others.

Despite the common name, squamous cell carcinomas arising in different body sites can show tremendous differences in their presenting signs and symptoms, natural history, prognosis, and response to treatment.


Hope this web-site helps

Greend's picture
Posts: 678
Joined: Feb 2010

Dr Thompson told me that my tonsil cancer was "aggressive growth that hits lymps and then normaally mets in the brain". This was 15 years ago.

Redbanker's picture
Posts: 36
Joined: May 2011

We were told that the next likely site would be the lungs.



ratface's picture
Posts: 1319
Joined: Aug 2009

It seems because of the routing of the lymphatic system it probably winds up in the lungs most often. The brain is probably next. Once in the lymph system it's got a ticket to ride. This can be awful stuff.

Skiffin16's picture
Posts: 8286
Joined: Sep 2009

As everyone has hit on, I think the lymphnodes are one of the key pathways for mets....depending on your original Dx, that could be potential for mets.

Time is always a factor also....

I have read reports and studies that the first two years are the greatest for recurrence. At five years the percentage for recurrence is lowest. But that after that, odds or percentages increase again by around 2% each year. This being as we get older the immune system gets less efficient.

Anyways, hoping we all live to be very old and pass at very old well lived life.


robinleigh's picture
Posts: 297
Joined: Mar 2011

for the replies. I too understood that the most common sites for metastasis were the lungs and brain. That's why we were so shocked when the recurrence was so quick and in the pelvic bone and femur. Oh well...either way...we're fighting tooth and nail with this second battle. The good news is that Andy has had no (as in zero) bone pain and evidently bone cancer is very painful. He is also tolerating the chemo very well so we're trying to remain hopeful that he can be in that percentage that beats it more than once. Lots of you are living proof of that and it sure gives us hope.
Thank you for always being there!

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