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Stage 4 progression when desease confined to peritoneum and lymph nodes

vodkamarty's picture
vodkamarty
Posts: 17
Joined: Jul 2010

Hear alot about progression and possible cure (surgery) when colon cancer has metastisized to the liver. Little information available as to progression, prognosis and possibility of long term control (or curative approach) when cancer is confined to peritoneum (lymph nodes) and currently asymtomatic.

Would appreciate any insight. Thanks!

-Marty

pepebcn's picture
pepebcn
Posts: 6352
Joined: Aug 2010

Just not the same!
Hugs!

mom_2_3
Posts: 964
Joined: Nov 2008

I am not overly familiar with that type of progression but if you Google "hipec" that may lead you in the direction you want to research.

Amy

Buzzard's picture
Buzzard
Posts: 3073
Joined: Aug 2008

Phillieg is all knowing about this center and with Hipec......I am sure that he will enter the scene with his expertise as well soon...Wishing the best for you is all I can do, I am more a rectal/lung patient/survivor and my knowledge base is more directed in that area....help is on the way though .......Buzz

kuastoi
Posts: 63
Joined: Apr 2009

As stated, the peritoneum and lymph nodes are not equivalent structures.

The peritoneum is the lining surface in you abdomen - covering all of the organs there. Lymph nodes are structures that arise along the drainage lymphatic system in your body, it allows plasma/fluid to drain back into the circulatory system while being filtered by the immune system along the way.

That being said, treatment to the peritoneum usually includes treatments like Hi-pec as has been described already here, essentially chemo into the peritoneal space sometimes with heat etc. From what I have read here on the board - it can be very effective but no personal experience.

With regard to the lymph nodes the treatment is usually confined to chemo (if the node is not taken out at the time of surgery on the bowel). Occasionally radiation therapy can help if the nodes is not near any vital structures and they can focus the beam there without any other local damage. this can be challenging in the chest and other places in the abdomen and there are few studies looking at the benefits of this approach.

I have learned all this as I have had one small nodule (now removed) on my omentum (part of the peritoneum) discovered on a second surgery in my belly (when I developed a perforated bowel due to avastin) and I have several large groups of lymph nodes in my chest and neck.

From my angle - it is almost easier to have liver or lung mets as surgeons are more amenable to resecting these when possible and Onc's radiate them if the can't be resected. They are more closed minded about nodes elsewhere due to the lack of experience with radiation and the difficulty in resecting them.

Hope this helps some

Tom

pepebcn's picture
pepebcn
Posts: 6352
Joined: Aug 2010

I been treated successfully of my retroperitoneum Lymph with a combination of Irinitecan-avastin and 45 days of radio and 5fu! It worked for the moment!.

vodkamarty's picture
vodkamarty
Posts: 17
Joined: Jul 2010

Hi Pepebcn,

Sent a response earlier, don't think it went through. If so, pardon the doubling up. Again, thanks for your feedback.

Did you have any cramping associated with your node? Had you been on either of these chemo regimes previously?

Glad you're doing well!

Best,

Marty

pepebcn's picture
pepebcn
Posts: 6352
Joined: Aug 2010

start with 5FU 24 h a day 45 days and 45 round of radio! For the moment no more chemo since everything has gone.
Hugs!

vodkamarty's picture
vodkamarty
Posts: 17
Joined: Jul 2010

Thanks Tom!

Good to get your experiences. CEA slowly rising (checked monthly) from low of 5 then 7 and now 17. PET shows very small suspicious node in lower left pelvis. Wife feels pretty good with just a little cramping in the area when exercising (might possibly be adheasions from previous surgery in area).

Agree, seems if you had to pick mets (who would?!) the liver would be the site for best chance of cure.

All the best to you!

-Marty

kuastoi
Posts: 63
Joined: Apr 2009

Sometimes I long for a simpler situation where they could just go in and hack them out and be done with it - but I'll push on and annoy the doc's until they come up with something I like.

With what your are describing above - it sounds like the node could be irradiated if it continued to be a problem. Good luck

Tom

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