Aug 10, 2010 - 12:09 am
She has completed 3/6 scheduled rounds of weekly carboplatin/taxol. Despite having a couple early setbacks (kidney failure treated with ureteral stents, and a deep vein thrombosis in her leg) she was doing was doing remarkably well with no major symptoms for the past couple of months up until a couple of weeks ago when the ascites started accumulating in her abdomen. Her CA125 numbers had gone down to normal and her CAT Scan one month ago showed marked improvement but in the past couple of weeks this ascites started and a follow up CAT Scan indicates increased cancer growth and omental caking
She had 2.3 liters drained (by paracentesis) from her abdomen less than a week ago and another 1 liter drained today. The paracentesis has relieved some of the nausea but she still has a distended abdomen and is horribly uncomfortable
Her doctors have concluded that the carboplatin/taxoll isn’t working and want to start her on Gemzar (gemcitabine) this week until functional profiling results come back.
We are having trouble finding information on abdominal ascites during treatment for endometrial cancer or treatment of resistant endometrial cancer abdominal ascites using Gemzar.
We are all very worried about these new symptoms and nervous about the switch in chemo. If anyone has any experience with ascites or being treated with Gemzar we would be very grateful for any information.