Why Does Hormone Therapy Have So Many Bad Side Effects?

survivorbc09
survivorbc09 Member Posts: 4,374 Member
edited March 2014 in Breast Cancer #1
Has anyone ever asked their oncologist this? I haven't yet, but, I will. There must be some

explanation. But what? Why would they all, more or less, have terrible side effects? Even

like tamoxifen, it can give you ovarian cancer. Does it all make sense? And, some of the

side effects will last your lifetime.

Comments

  • lynn1950
    lynn1950 Member Posts: 2,570
    Good question
    My fingers are so stiff from Arimidex. It would be nice to know why. x0x0x0 Lynn
  • susie09
    susie09 Member Posts: 2,930
    lynn1950 said:

    Good question
    My fingers are so stiff from Arimidex. It would be nice to know why. x0x0x0 Lynn

    That is a good question. I
    That is a good question. I am suppose to start on tamoxifen, but, I don't think I will. I think I will just pass on it. I don't like the sound of the side effects and the fact that it can give you ovarian cancer, and, I am not having my ovaries out. My percentage was really low with it anyway.

    Hope your fingers feel better someday Lynn!
  • Akiss4me
    Akiss4me Member Posts: 2,188
    I think....
    Even though there are side effects with all treatments, sometimes it is still better than the alternative. We have not yet gotten to the point of inventing a magic cure that effects cancer and cancer only. Unfortunately, cancer is still made up of the same cells that the rest of our body has....just mutated. Attack the cancer cells, you have no choice but to attack the good cells too. There is a risk with ANYTHING you put into your body because it depends on how your body reacts to that substance no matter if it is food or drug. It doesn't make sense, does it? :) Pammy
  • tasha_111
    tasha_111 Member Posts: 2,072
    Akiss4me said:

    I think....
    Even though there are side effects with all treatments, sometimes it is still better than the alternative. We have not yet gotten to the point of inventing a magic cure that effects cancer and cancer only. Unfortunately, cancer is still made up of the same cells that the rest of our body has....just mutated. Attack the cancer cells, you have no choice but to attack the good cells too. There is a risk with ANYTHING you put into your body because it depends on how your body reacts to that substance no matter if it is food or drug. It doesn't make sense, does it? :) Pammy

    Wondering
    I am wondering if I should continue with the tamoxifen. Does the bad outweigh the good? My onco will not discuss this with me.. so I guess I'll have to carry on researching it myself and then decide. Jxxxxxxx
  • confused123
    confused123 Member Posts: 251
    tasha_111 said:

    Wondering
    I am wondering if I should continue with the tamoxifen. Does the bad outweigh the good? My onco will not discuss this with me.. so I guess I'll have to carry on researching it myself and then decide. Jxxxxxxx

    Everything causes cancer.

    Everything causes cancer. Chemo and rads can even can cause it. I have to take Tamoxifen and am getting nervous about it now. I will ask many questions when that time comes. I start the Tamoxifen after rads.

    Tasha I can't believe the doc won't discuss it with you. That is crazy. Be careful where you research. I can let you know what my doc tells me.

    Kim
  • Kat11
    Kat11 Member Posts: 1,931 Member

    Everything causes cancer.

    Everything causes cancer. Chemo and rads can even can cause it. I have to take Tamoxifen and am getting nervous about it now. I will ask many questions when that time comes. I start the Tamoxifen after rads.

    Tasha I can't believe the doc won't discuss it with you. That is crazy. Be careful where you research. I can let you know what my doc tells me.

    Kim

    I really do not know much
    I really do not know much about all this stuff we have to do in order to save our life, but I can tell you this. My Mother had breast cancer in 1970's. She refused Chemo and Rads. However she took the 5 year pill which I believe is Tamoxifin. I believe the drug started with a N. She was a breast cancer survivor of over 15 or more years. Died from a new cancer ( from smoking ) lung.
  • maya00i
    maya00i Member Posts: 42
    lynn1950 said:

    Good question
    My fingers are so stiff from Arimidex. It would be nice to know why. x0x0x0 Lynn

    I take Arimedex too.
    I take Arimedex too. Everytime I have a pain,can not sleep,bumps on fingers etc.I am told it's the Arimedex.
  • lynn1950
    lynn1950 Member Posts: 2,570
    susie09 said:

    That is a good question. I
    That is a good question. I am suppose to start on tamoxifen, but, I don't think I will. I think I will just pass on it. I don't like the sound of the side effects and the fact that it can give you ovarian cancer, and, I am not having my ovaries out. My percentage was really low with it anyway.

    Hope your fingers feel better someday Lynn!

    Thanks, Susie
    I asked my onc on Wednesday if it was permananet but...(and I will attribute this to chemobrain and not early onset Alzheimer's) , I don't remember his answer! :) Lynn
  • lynn1950
    lynn1950 Member Posts: 2,570
    tasha_111 said:

    Wondering
    I am wondering if I should continue with the tamoxifen. Does the bad outweigh the good? My onco will not discuss this with me.. so I guess I'll have to carry on researching it myself and then decide. Jxxxxxxx

    continuing
    Julia, are you a candidate for an AI (post-menopausal). I just mentioned sweats, insomnia, and stiff fingers to my oncs on Wednesday and they were explaining the alternative medications and the consequences of switching! I wasn't even complaining or thinking about stopping or switching.... Consider switching oncs? As you used to sign-off...(I'm a copycat when the cause is right) xoxoxoxo Lynn
  • DianeBC
    DianeBC Member Posts: 3,881 Member
    I am also considering on not
    I am also considering on not taking tamoxifen because of the side effects. Tamoxifen, from what I know, was in clinical trial stage in the late 80's in the United States. Its use had been to treat infertility in women and body builders even took it and some still do. It was also used to treat other conditions, from what I know. It is listed by the ACS as a known carcinogen. Two of the most serious side effects are uterine cancer/endometrial cancer and blood clots. When I found out that the American Cancer Society had it listed as a carcinogen, that pretty much made my mind up. I will probably go without it. To me, it isn't worth the risk.

    Good luck to all of you!
  • Kylez
    Kylez Member Posts: 3,761 Member
    DianeBC said:

    I am also considering on not
    I am also considering on not taking tamoxifen because of the side effects. Tamoxifen, from what I know, was in clinical trial stage in the late 80's in the United States. Its use had been to treat infertility in women and body builders even took it and some still do. It was also used to treat other conditions, from what I know. It is listed by the ACS as a known carcinogen. Two of the most serious side effects are uterine cancer/endometrial cancer and blood clots. When I found out that the American Cancer Society had it listed as a carcinogen, that pretty much made my mind up. I will probably go without it. To me, it isn't worth the risk.

    Good luck to all of you!

    I am also not taking tamox
    I am also not taking tamox yet. I am still undecided and my oncologist says it is up to me. I am just not sure I want to risk it. So many women on it have had so many gynocological problems and had to have hysterectomies, which could have been the uterine cancer starting in them. And, I don't want that. That is one surgery that I can do without. I know several that had that and it only caused more surgery's to be done. Their bladder's fell and had to have surgery to tie it back up. Just too many risks possibly to consider.
  • survivorbc09
    survivorbc09 Member Posts: 4,374 Member
    Kylez said:

    I am also not taking tamox
    I am also not taking tamox yet. I am still undecided and my oncologist says it is up to me. I am just not sure I want to risk it. So many women on it have had so many gynocological problems and had to have hysterectomies, which could have been the uterine cancer starting in them. And, I don't want that. That is one surgery that I can do without. I know several that had that and it only caused more surgery's to be done. Their bladder's fell and had to have surgery to tie it back up. Just too many risks possibly to consider.

    Seems like a lot of us
    Seems like a lot of us question the hormone therapy and the side effects. It is a very controversial subject. I don't know. I just don't see that it is worth even a small chance of getting another cancer. Seems like a lot of women do just fine with no recurrence without taking it. It is just a personal decision for all of us.
  • DianeBC
    DianeBC Member Posts: 3,881 Member
    tasha_111 said:

    Wondering
    I am wondering if I should continue with the tamoxifen. Does the bad outweigh the good? My onco will not discuss this with me.. so I guess I'll have to carry on researching it myself and then decide. Jxxxxxxx

    Tasha, you should insist
    Tasha, you should insist that your oncologist discuss tamoxifen with you. There are so many side effects and I thought he was required to explain them to you by law. But, maybe not. But, any good oncologist would let you know everything, or, as much as he knows, which would entail the se's. I know many take tamox and lots don't. It is just one of those personal decisions that one makes. I guess I just don't see the good in it personally for me.

    But, I do hope you see another oncologist Tasha. You deserve to be treated better than with the one you see.

    Diane :)
  • sausageroll
    sausageroll Member Posts: 415

    Seems like a lot of us
    Seems like a lot of us question the hormone therapy and the side effects. It is a very controversial subject. I don't know. I just don't see that it is worth even a small chance of getting another cancer. Seems like a lot of women do just fine with no recurrence without taking it. It is just a personal decision for all of us.

    Get good advice
    It's right that everyone has to make their own decision and weigh the pros and cons..but to do that you need an oncologist who will dicuss it with you. Don't listen to too many scare stories though..that's why you need a professional to give you the details. I am just starting Femara which is given to post menopausal women only. I know there are side effects, but for me I want to do everything I can to prevent this coming back.
    Good luck with your decision.
  • survivorbc09
    survivorbc09 Member Posts: 4,374 Member
    I saw someone post on here
    I saw someone post on here that they have no side effects with tamoxifen. My oncologist said that if you have no side effects with it, then you probably are not metabolizing it and it might not be working. They have a test to see if you can metabolize it. Oncologists use it a lot. My percentage of a recurrence without taking it is so small that it really isn't worth it for me, like it might be with someone who has a higher percentage. I just wish everyone good luck on it.
  • Alexis F
    Alexis F Member Posts: 3,598

    I saw someone post on here
    I saw someone post on here that they have no side effects with tamoxifen. My oncologist said that if you have no side effects with it, then you probably are not metabolizing it and it might not be working. They have a test to see if you can metabolize it. Oncologists use it a lot. My percentage of a recurrence without taking it is so small that it really isn't worth it for me, like it might be with someone who has a higher percentage. I just wish everyone good luck on it.

    That is true, as far as I
    That is true, as far as I know. If you have no side effects with tamox, then you probably are not metabolizing it and therefore, it is doing no good for you.

    There is a test to see if you do metabolize it. I thought all oncologist's offer it. It would make sense to.
  • Noel
    Noel Member Posts: 3,095 Member
    Alexis F said:

    That is true, as far as I
    That is true, as far as I know. If you have no side effects with tamox, then you probably are not metabolizing it and therefore, it is doing no good for you.

    There is a test to see if you do metabolize it. I thought all oncologist's offer it. It would make sense to.

    I have been putting tamox
    I have been putting tamox off and think I will just put it off forever. lol

    My percentage is so small of it helping me, that I don't think it is worth even taking the chance of the se's.

    Noel