Prayers now please.

jimwins said:

Hi Michelle

You two have been on my mind and thank you for the update. I'm glad you have a plan and alternatives.   I don't have experience with GVD so I can't give you first hand information other than what I could research.  It's amazing how far they have come with genetic research and where it's going.  Hopefully Kyle's brother will be an exact match but it's nice to know they're likely to find a match otherwise.

We love you guys and please know we are here for you.  Tell Kyle, he's welcome to chat with us. 

God bless and keep you both.

Hugs - Jim

 

 

     It is such a relief to know that Kyle's situation is hopeful.  We have been so worried.  Bill and I were talking about you last night.  It sounds like you are in very good hands and that they are staying up with everything out there in the research field.  Look at what happened with Bill.  They had nothing permanent for relapsed MCL and then 3 months before his relapse they took his lifesaver drug out of trials.  You have much to be hopeful for, it seems lymphoma is in the forefront of many studies.  It sounds like Kyle's doctors are not leaving a stone unturned.  Thank you for updating us, we know your minds are on other things, so we don't expect too much posting from you, and we all understand.  Keep fighting and we will keep you in our thoughts and prayers.  Our best to your families also.

Love, Becky & Bill

MChantal said:

Hello my family and friends

We are currently in Rochester, MN at the Mayo Clinic receiving the game plan for Kyle's upcoming treatment. I truly appreciate all of your comments and responses. I am too blessed to have you all in our lives. I guess in a way you can say that Kyle and I are at "peace" with the relapse. It is just getting a bit scary tho because they are calling his lymphoma "unusual" now. I understand all T-cell lymphoma's are unusual yet, it's not something we really want to hear. In which, I am taking it as they're paying more attention to him. 

Kyle will begin chemo next week. This time they will be doing GVD. For those of you who may have had the GVD regime. How was your experience? I know it's somewhat the same severity of the CHOP-E yet, has different administeration dates and etc. He will have two rounds and after the two rounds we will return back to the Mayo to see where is progress is. I am hopeful that the chemo will work for him considering he did respond so beautifully to CHOP-E. However, they did indicate that there is a 50/50 chance he may or may not respond. Faith and hope, he will! I know it. If not, they will switch his chemo to a new regime being ICE or DHAP.  After we reach remission again (we will), Kyle will undergo an allogeneic stem cell transplant. They are currently testing his older brother to be a donor and if his brother is not an exact match they will search for the unrelated donor. Given his ethnicity, he has a 70% chance of finding a donor, if need be. Thank you Lord. The Mayo has also signed Kyle into a clinical protocol called CIM.  The clinical protocol will be pulling the Lymphoma from his bone marrow and looking he genetic make-up of the type of Lymphoma he has in hopes they can find some specific drug that may help reduce the cancer. It is quite amazing and we are hopeful that they will find something specific in the genetic background of that dirty cancer to kill it completely!

I have a gut feeling that everything will be okay. God has a plan and for some bizarre reason he has chosen Kyle and our family to undergo this specific plan. As long as He continues to be with us through this, we will be okay.

I appreciate and love you all. Please continue to pray for Kyle and our family.

I'm glad that everything is moving fast for Kyle and you! I know how worried you must be but your faith will get you both through this. I will continue to keep you both in my prayers...I can exhale now, I think we were all holding our breath for your response! Glad it's a positive one!!! Take care sweetie and keep us posted when you can (((Hugs)))

Sincerely,

Liz

Praying for you guys. 

MChantal said:

I cherish

You all. Just reading through all these past posts and I am just so grateful for you all. I do not think I could ever say this enough but, thank you all.

Kyle and I are doing well. We are expected to start GVP (correction from last post) regime this upcoming week until than, we are just going with the flow of life, attempting to keep busy and not allow stupid cancer to dictate our lives. Stupid cancer!

Interestingly and strangely enough, Kyle's symptoms have subsided. He has not had a fever, no night sweats, no body aches, the welts are gone and he "doesn't feel sick." They did bilateral bone marrow biopsies at the Mayo Clinic and of course, the pathology report is beyond confusing yet, I do want to quote one part that is comparing the biopsy obtained here at home (7/31/2014) to the biopsies at the Mayo (8/21/2013). 

"Previous specimen's (7/31/2014) were stensively reviewed together with the current specimen (8/21/2014). The tumor cells in the previous two specimens exhibit intermediate to large in size, irregular to convoluted and elongated nuclei, variable prominent nucleoli and scant deep basophilic cytoplasm with fine eosinophilic granules. They are positive for CD8 immunohistochemical study with distinct golgi staining. The neoplastic cells are only occasionally present in the current specimen. The difference in tumor burden between the current (8/21/2014) and previous specimen (7/31/2014) may responset a sampling bias. Clinical correlation is suggested."

Yes, it could potentially be a sampling bias. Yet, the fact that Kyle's symptoms have basically disappeared and the cancer cells are only "occasionally" present in the biopsy now. What could this mean? I believe in miracles, I really do. And, I know not to get my hopes up but..could it be possible that Kyle's immune system is fighting back even tho it is his immune system that "has" cancer. I may be going crazy too. Lol. I guess we will find out more next week when he get's his blood work done.

I hope you all are doing well. You all deserve it.

Kyle and I went to a benefit last weekend for Presbyterian Hospital supporting Childhood Psychiatry. The theme was the Roaring 20s. It was too fun! We should have been born in that era to dress up everyday! Lol

 

 

Michelle and Kyle,

I cherish you too. You both look fantastic dressed in the looks of the era. BUT, let us be thankful for living in the here and now for the blessings of research science and the progress in treatments for our disease.

I am so thankful that Kyle is feeling better and that his symptoms have subsided. I believe in miracles too!

I will keep praying for you both. You are such a gorgeous couple and such an inspiration.

Much love,

Rocquie

DadysGirl said:

Loved seeing you both

Loved seeing you both smile... I'm sorry I can't write much these days... Please keep us posted hopefully with more great news...

We are very happy with your news.  I don't quite know what to think either, it seems amazing and unbelieveable.  I understand why you don't want get your hopes up and that is wise, but my goodness, that is, like you said, crazy!  Well, Bill is testimony that things can turn around.  For us it was all timing and the new target drug, but it shows us never to give up hope and never quit the fight.  All of us have been so worried, I have been messaging some personally and we have been very concerned.  Thank you for letting us share your promising news and please let us know what you find out next week.  BTW, you both look like the Belle and Beau of the ball.  Yes, that must have been quite the day.  I am sure, as with us on the forum, you have been a real example and encouragement to your community. 

Love and prayers always,

Becky & Bill