Overview of the management of stage 1 UPSC

I found this article today and thought it provided an excellent overview of the treatment protocols and outcome for women with Stage 1 UPSC:

The link is:


http://www.isrn.com/journals/obgyn/2011/146264/
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Comments

  • glammy
    glammy Member Posts: 4
    thanks
    really good article.

    I had the earliest finding ever, and my case was presented. they had no recommendation for me in the Northeast cancer symposium so I asked my kids. Now, after reading your link, I'm very glad I chose to get the six rounds of chemo. yay! Thanks again
  • minniejan
    minniejan Member Posts: 88
    glammy said:

    thanks
    really good article.

    I had the earliest finding ever, and my case was presented. they had no recommendation for me in the Northeast cancer symposium so I asked my kids. Now, after reading your link, I'm very glad I chose to get the six rounds of chemo. yay! Thanks again

    Thanks
    Thanks for posting!

    With stage 1 UPSC has anyone been treated with three rounds of chemo (carboplatin and taxol) three weeks apart, with brachytherapy administered three times (total) between the rounds of chemo? As my oncologist said, hit it hard and hit it fast. I always read about sandwich protocol but not what I received.
  • bots
    bots Member Posts: 53
    Thanks so much
    Thank you so much for this link. I was diagnosed with Stage 1a UPSC in July, 2009. Actually, at the time of my diagnosis the stage was considered 1b, but it changed with the new FIGO ratings. I was treated with three rounds of chemo but no radiation. This month I passed the two-year post-treatment mark with no recurrence. My oncologist said that usually if one with Stage 1a UPSC doesn't recur in two years, one probably wouldn't have a recurrence. I still hold my breath every time I think about it, which is often. This review of studies will help me breathe easier.
  • Kaleena
    Kaleena Member Posts: 2,088 Member
    Thanks for the article
    Thanks for the article Jill.

    Also, I might add, what a lovely photograph. It looks like you are enjoying yourself somewhere in Manhattan?

    Kathy
  • Rewriter
    Rewriter Member Posts: 493 Member
    bots said:

    Thanks so much
    Thank you so much for this link. I was diagnosed with Stage 1a UPSC in July, 2009. Actually, at the time of my diagnosis the stage was considered 1b, but it changed with the new FIGO ratings. I was treated with three rounds of chemo but no radiation. This month I passed the two-year post-treatment mark with no recurrence. My oncologist said that usually if one with Stage 1a UPSC doesn't recur in two years, one probably wouldn't have a recurrence. I still hold my breath every time I think about it, which is often. This review of studies will help me breathe easier.

    Bots
    If it helps you breathe even MORE easily, my oncologist agrees with your oncologist in thinking that Stage 1a UPSC that doesn't recur in two years probably will not recur. Best of luck to you.
  • Rewriter
    Rewriter Member Posts: 493 Member
    Kaleena said:

    Thanks for the article
    Thanks for the article Jill.

    Also, I might add, what a lovely photograph. It looks like you are enjoying yourself somewhere in Manhattan?

    Kathy

    Kathy
    Thanks for the compliment on the photo; I had to replace it because I did not consult my friend about posting her picture on the Internet. Yes, a small group of us were having a lovely time at brunch in...BROOKLYN. Yes, Brooklyn has become a happening place. I lived in Manhattan for about 35 years; but now when I am in "the city" and travel back home, I am soothed by the quiet and the green grass and flowers. Plus, all of my neighbors know who I am; whereas, in the Manhattan building, people lived together for years without knowing anything about each other.

    I love the expression on your dog's face. Was he or she trying to understand what you were saying?

    Jill
  • Kaleena
    Kaleena Member Posts: 2,088 Member
    Rewriter said:

    Kathy
    Thanks for the compliment on the photo; I had to replace it because I did not consult my friend about posting her picture on the Internet. Yes, a small group of us were having a lovely time at brunch in...BROOKLYN. Yes, Brooklyn has become a happening place. I lived in Manhattan for about 35 years; but now when I am in "the city" and travel back home, I am soothed by the quiet and the green grass and flowers. Plus, all of my neighbors know who I am; whereas, in the Manhattan building, people lived together for years without knowing anything about each other.

    I love the expression on your dog's face. Was he or she trying to understand what you were saying?

    Jill

    My Dog
    My Dog Misty turned 1 yr old in June. She just loves to play and be happy as you can see on her face. She's a good dog.

    I hope to get to NY soon. My husband and I usually make a yearly trip
    but we missed it this year. We live in a rural area but like to make the
    Big City trip to see the sights!

    My best to you!

    Kathy
  • sleem
    sleem Member Posts: 92
    Kaleena said:

    My Dog
    My Dog Misty turned 1 yr old in June. She just loves to play and be happy as you can see on her face. She's a good dog.

    I hope to get to NY soon. My husband and I usually make a yearly trip
    but we missed it this year. We live in a rural area but like to make the
    Big City trip to see the sights!

    My best to you!

    Kathy

    Info, some repeat for Stage 1A
    The first two links are articles to understand more about UPSC & CA-125.

    C:\UPSC\Frequently Asked Questions (FAQ) about the CA-125 Test good.mht

    http://www2.mdanderson.org/depts/oncolog/pdfs-issues/10/oncolog4-5-10.pdf

    See (pp.4-6) in the article. Even though it is for early stages, it has a good background of UPSC and the treatments that are being considered for women in general. This is the treatment that I had at MDA.


    I have found these articles are helpful in understanding stages in UPSC.
  • Gracegoi
    Gracegoi Member Posts: 59
    sleem said:

    Info, some repeat for Stage 1A
    The first two links are articles to understand more about UPSC & CA-125.

    C:\UPSC\Frequently Asked Questions (FAQ) about the CA-125 Test good.mht

    http://www2.mdanderson.org/depts/oncolog/pdfs-issues/10/oncolog4-5-10.pdf

    See (pp.4-6) in the article. Even though it is for early stages, it has a good background of UPSC and the treatments that are being considered for women in general. This is the treatment that I had at MDA.


    I have found these articles are helpful in understanding stages in UPSC.

    Late night reading yields facinating results!

    Jan.

    This is a really good attempt at rounding up all the research done on stage one over the years.

    All 300 plus ladies over ten plus years.

    There is something about reading these studies that makes me feel like I'm watching a Wimbeldon tennis match while putting together a jigsaw puzzel on the side.

    In one of the studies I was reading

    " The majority of the patients (19/29) recurred in the abdomen, vagina, or pelvis (66%"

    I nearly jumped out of my chair as I read the last word. Blinked twice and thought

    "I didn't know MEN could get pappillary serous!"

    I had to reread it and ...well ...

    I misread the last word.


    ;-)
  • daisy366
    daisy366 Member Posts: 1,458 Member
    Gracegoi said:

    Late night reading yields facinating results!

    Jan.

    This is a really good attempt at rounding up all the research done on stage one over the years.

    All 300 plus ladies over ten plus years.

    There is something about reading these studies that makes me feel like I'm watching a Wimbeldon tennis match while putting together a jigsaw puzzel on the side.

    In one of the studies I was reading

    " The majority of the patients (19/29) recurred in the abdomen, vagina, or pelvis (66%"

    I nearly jumped out of my chair as I read the last word. Blinked twice and thought

    "I didn't know MEN could get pappillary serous!"

    I had to reread it and ...well ...

    I misread the last word.


    ;-)

    LOL
    ya know, Grace. Even before I read your last sentence, I had to re-read those stats!!! I think I read it the same as you!!! Laughter fights cancer too!!

    Take care. Mary Ann
  • bots
    bots Member Posts: 53
    sleem said:

    Info, some repeat for Stage 1A
    The first two links are articles to understand more about UPSC & CA-125.

    C:\UPSC\Frequently Asked Questions (FAQ) about the CA-125 Test good.mht

    http://www2.mdanderson.org/depts/oncolog/pdfs-issues/10/oncolog4-5-10.pdf

    See (pp.4-6) in the article. Even though it is for early stages, it has a good background of UPSC and the treatments that are being considered for women in general. This is the treatment that I had at MDA.


    I have found these articles are helpful in understanding stages in UPSC.

    Sleem
    Sleem, When you had your treatment at MDA, did you by any chance know Dr. Liz Han? My oncologist retired last year and Dr. Han replaced him. I like both doctors but they are very different in their approaches.
  • Betye
    Betye Member Posts: 1
    minniejan said:

    Thanks
    Thanks for posting!

    With stage 1 UPSC has anyone been treated with three rounds of chemo (carboplatin and taxol) three weeks apart, with brachytherapy administered three times (total) between the rounds of chemo? As my oncologist said, hit it hard and hit it fast. I always read about sandwich protocol but not what I received.

    Stage 1 UPSC
    I was recently diagnosed and began treatment for stage 1 UPSC in Aug. 2011. I have recovered nicely from my complete hysterectomy and am in my 1st of 3 chemo treatments with carboplatin and taxol. My hair is just starting to fall out, but my head is in a good place. I am happy to nail this fast and furiously.

    I am scheduled for only 3 rounds and no radiation thus far. Is the CA 125 the only way they tell if it returns?

    Its good to read those articles. I feel encouraged.
  • bots
    bots Member Posts: 53
    Betye said:

    Stage 1 UPSC
    I was recently diagnosed and began treatment for stage 1 UPSC in Aug. 2011. I have recovered nicely from my complete hysterectomy and am in my 1st of 3 chemo treatments with carboplatin and taxol. My hair is just starting to fall out, but my head is in a good place. I am happy to nail this fast and furiously.

    I am scheduled for only 3 rounds and no radiation thus far. Is the CA 125 the only way they tell if it returns?

    Its good to read those articles. I feel encouraged.

    Betye
    Betye, I was also diagnosed with Stage 1a UPSC, and I had only 3 rounds of the carboplatin. My oncologist said I would have three or four rounds, but if I started having a lot of neuropathy they would stop at three. Usually you will have CT scans once or twice a year, depending on your oncologist. That, the CA 125 and the physical exam as well as symptoms you may have such as bleeding or pain that, as my oncologist said, "Is there in the morning and is still there at night," are some ways one looks for a recurrence. Some of the other ladies might have additional information.


    I am past the two-year point with no return, so things are good. I hope the same for you.

    Bots
  • Gracegoi
    Gracegoi Member Posts: 59
    bots said:

    Sleem
    Sleem, When you had your treatment at MDA, did you by any chance know Dr. Liz Han? My oncologist retired last year and Dr. Han replaced him. I like both doctors but they are very different in their approaches.

    Hi Mary Ann and for Sleem
    Mary Ann,

    You read my mind. I got such a big laugh I had to share it . I then laughed some more. The real life experince showed me the importance of laughter in the midst of such serious study.

    Later I got embarraced and was afraid some might find it offensive.

    They have Yoga laughter in my town. I just have not gotten up the courage to check it out.


    Sleem your first link does not work. I did a bit of fiddling and I belive I found it?

    http://www.moffitt.org/CCJRoot/v16n1/pdf/46.pdf


    Grace
  • daisy366
    daisy366 Member Posts: 1,458 Member
    Gracegoi said:

    Hi Mary Ann and for Sleem
    Mary Ann,

    You read my mind. I got such a big laugh I had to share it . I then laughed some more. The real life experince showed me the importance of laughter in the midst of such serious study.

    Later I got embarraced and was afraid some might find it offensive.

    They have Yoga laughter in my town. I just have not gotten up the courage to check it out.


    Sleem your first link does not work. I did a bit of fiddling and I belive I found it?

    http://www.moffitt.org/CCJRoot/v16n1/pdf/46.pdf


    Grace

    Grace
    Laughter yoga is a great thing!!! I need to get back to that class. With all the talk of prevention and treatment of cancer, I think laughter should be on that list!!

    Best to you. Mary Ann
  • Rewriter
    Rewriter Member Posts: 493 Member
    daisy366 said:

    Grace
    Laughter yoga is a great thing!!! I need to get back to that class. With all the talk of prevention and treatment of cancer, I think laughter should be on that list!!

    Best to you. Mary Ann

    Never mind
    never mind
  • Gracegoi
    Gracegoi Member Posts: 59
    Rewriter said:

    Never mind
    never mind

    what a night that was!
    Sorry Jill,

    I was close though. ;-) I tried to edit your name but its too late.
  • sleem
    sleem Member Posts: 92
    bots said:

    Sleem
    Sleem, When you had your treatment at MDA, did you by any chance know Dr. Liz Han? My oncologist retired last year and Dr. Han replaced him. I like both doctors but they are very different in their approaches.

    Hello bots
    Just reading some threads on here. No, I did not. I've had one Dr. & read articles from others at MDA posted on the web. Mine is gyn/onco combo.
  • janefa
    janefa Member Posts: 1
    minniejan said:

    Thanks
    Thanks for posting!

    With stage 1 UPSC has anyone been treated with three rounds of chemo (carboplatin and taxol) three weeks apart, with brachytherapy administered three times (total) between the rounds of chemo? As my oncologist said, hit it hard and hit it fast. I always read about sandwich protocol but not what I received.

    I am now trying to decide
    I am now trying to decide what to do next. My Dr reccommends the "sandwich tx" I was diagnosed with papilllary serous endometrial Ca in Nov 2011 I had robotic assisted complete hysterectomy with removal of fallopian tubes, ovaries, box of lymp nodes and part removal of the omentum. I am 67 and have other health concerns including asthma, diabetes, overweight I am worried that the treatment is worse that the chance of recurrance. DO you have any infor about recurrance with just the above surgery and no further tx? Any info would be appreciated. Thanks
  • debrajo
    debrajo Member Posts: 1,095 Member
    janefa said:

    I am now trying to decide
    I am now trying to decide what to do next. My Dr reccommends the "sandwich tx" I was diagnosed with papilllary serous endometrial Ca in Nov 2011 I had robotic assisted complete hysterectomy with removal of fallopian tubes, ovaries, box of lymp nodes and part removal of the omentum. I am 67 and have other health concerns including asthma, diabetes, overweight I am worried that the treatment is worse that the chance of recurrance. DO you have any infor about recurrance with just the above surgery and no further tx? Any info would be appreciated. Thanks

    other issues also
    I had the same concerns with other health problems also. I had to have open-heart surgery Sept 29,09 and the cancer surgery was Dec.5, 09. I also am over weight, with pill controled diabetes, not to mention high blood pressure. I have 1a and had all the surgerys,five rounds of radiation and six rounds of Taxol-carboplatan. So, so far I am 19 months clear. I will be 60 this month. The radiation and the chemo were not that bad for me. I even GAINED weight! I would do the treatment all over again if I had to. Hope this helps. Please contact me by e-mail if you want since I am not on every day.