Jun 24, 2014 - 8:41 pm
My husband and I are having a very difficult decision to make: To harvest eggs and freeze embryos before radiation and tamoxifen treatment; Or to do IVF after two year's of tamoxifen and restart on tamoxifen after giving birth. Hope to hear what you think, especially if you have similar experiences.
So here are my stories: I am 35 years old. During the last six years, I had four failed pregnancies, with fetus having chromosomal abnormality. Now the safest way for us to have a healthy baby is probably IVF. When I was getting ready to do IVF, I was diagnosed with stage 1a Left breast invasive mucinous carcinoma (Estrogen: positive; Progesterone: positive, Her2eu- protein, negative). I recently had lumpectomy and everything went well. No lymph node was involved. Since my oncotype score is low (11), the medical oncologist does not recommend chemo.
Now I will start radiation pretty soon. To preserve my fertility, I can have my eggs harvested and fertilized now, then freeze some embryos for IVF later. Ideally, the time would be after five years treatment on tamoxifen. Since the eggs are harvested and fertilized when I am 35 years old, the success rate won't drop dramatically even when I transplant the embryos at the age of 40. The fertility specialist feels ok with this plan. However, the medical oncologist does not feel safe enough for me to do the egg harvesting at this point. I do not need to have chemo, radiation won't affect my fertility. He is more comfortable to let me do IVF after radiation and two years of tamoxifen, then stop the drug, get pregnant, restart on tamoxifen after giving birth.
So really hope we can get some wisdom from you.