CSN Login
Members Online: 2

Remove ovaries?

helen e's picture
helen e
Posts: 223
Joined: Sep 2009

I am on the fence about what I should do. I stop taking Tamoxifen in December. I have been thinking about having my ovaries removed. I am 48 and still having my cycle. I worry about letting estrogen back in my body because my cancer was ER positive. Has anyone had their ovaries removed because of this? Thoughts, questions, concerns, advice? 

Josie21
Posts: 373
Joined: Nov 2012

I was ER positive and was on tamoxifen for two and a half years when my gynecologist suggested that I have a hysterectomy (everything removed except the cervix).  I had a couple of ovarian cysts that I kept getting checked until finally my doctor said she would feel better if we didn't take any chances.  I was 46 and she said the tamoxifen pretty much shut down my ovaries already.  I have to say, it was the best thing I ever did.  I had the surgery done laproscopically and I did really well.  I know every one is different, but I felt great right away.  One night in the hospital and the next day I was walking around.  In my case, the ovarian cysts made my decision easy, but knowing the peace of mind I felt afterwards, I would have done it no matter what.  If you have any questions, feel free to send me a message.  

Hugs,

Ginny

TraciInLA's picture
TraciInLA
Posts: 1873
Joined: Jul 2009

Helen,

I'm 45, and Aunt Flo still visits every month like the moon.  I also was strongly ER positive -- after I finished treatment, I assumed I should start thinking about having my ovaries removed, but both my gynecologist and my oncologist were strongly against this, because ovaries help protect your heart.  Even if they shut your ovaries down with Lupron injections (which we've also discussed), and even once you've gone through menopause, just having them in your body still seems to have the protective effect.

This is a particular concern for me, because I have a history of heart disease in my family.

So please talk with your doctors carefully about this, and ask them what your options are.  I'm curious that you're scheduled to stop taking Tamoxifen in December -- based on some large, well-respected studies that have been published in the last year, the standard of care is now tending toward 10 years on Tamoxifen, not 5.  My oncologist is recommending 10 years for nearly all his patients, unless they have particular risk factors.  

So maybe you don't need to stop taking Tamoxifen after all?

Just some issues to talk with your doctors about -- I always think it's good to get more than one opinion on these things, from your oncologist, your gynecologist, your surgeon -- whoever you like and trust.

Don't know if that helps?

Traci

Alexandra's picture
Alexandra
Posts: 1289
Joined: Jul 2012

Hello Helen,

Because you had breast cancer in pre-menopausal age and especially because it was ER-positive, it is highly unlikely that it was hereditary. But not impossible.

If you haven't yet been tested for BRCA 1/2 I recommend getting tested.

If you're BRCA-negative, I think you should keep your ovaries and go through natural menopause for the reasons Traci brought up. Surgical menopause is acute and overnight brings new very unpleasant symptoms, even more so if you can't take HRT like I do.

But if like me you are BRCA-positive, get your ovaries and fallopian tubes surgically removed as soon as possible to reduce your risk of ovarian cancer.

Good luck with whatever you decide to do.

Alexandra

Double Whammy's picture
Double Whammy
Posts: 2370
Joined: Jun 2010

with your oncologist.  This is obviously both a medical and a personal decision.  Having your ovaries removed is surgery and the risk needs to be worth the benefit.  It sounds like your goal is to prevent estrogen production, not to prevent ovarian cancer?  Just want to say that even us old ladies without ovaries or being postmenopausal, are on hormone deprivation therapy (typically an aromotase inhibitor, but I'm actually on Tamoxifen).  Just because our ovaries are gone, or are there and not producing estrogen, doesn't mean we don't have any.  We do.  It comes from our fat cells and is converted to estradiol that acts like estrogen.  So removing your ovaries alone would probably not prevent the effects of estrogens and if any hungry cells are on standby, you will still be producing some fuel for them.  At age 48, you're nearing natural menopause and your ovaries will stop producing estrogen in relatively short order on their own.

It's such a Catch 22.  If you keep your ovaries, they're going to make estrogen for a few more years, and you could develop ovarian cancer.  And who knows whether they're going to or not?  Alexandra's suggestion of the BRCA testing is worthwhile discussing with your oncologist for sure.  And maybe even getting more than one opinion, because that's probably all it is (unless you have the BRCA gene) - a guess based on statistics.  Did you take Tamoxifen for 10 years?  I believe tht is the current recommendation from San Antonio.  If you only took it for 5, it would be worthwhile discussing that option vs. removing ovaries.  5 more years would probably get you through menopause. 

You must also still have your uterus since you're still having menstrual periods.  I've had both breast and uterine cancers, both were estrogen dependent.  Both were diagnosed 5 years AFTER menopause.  Not just ovaries to worry about . . . but the odds continue to diminish as the years go by.  Hope you're getting your uterine lining checked regularly while on Tamoxifen because it is known to cause uterine/endometrial cancer. 

Good luck with your quest.  I'm not sure that you will get a definite answer.  Just do plenty of research so you can ask really good questions when you discuss this with your oncologist.  You need to be satisfied that you make the right decision for you and not look back.

Suzanne 

disneyfan2008
Posts: 5591
Joined: Oct 2010

NO advice (I hadf total hystercomty due to enlrage uterus side effect-so I told DR TO TAKE it all..antything that could come out at the same time)

 

I am thinking of you...

Denise

Maggie_Ann1
Posts: 10
Joined: Jan 2014

I don't know if this will help, but my ovaries were removed when I was 47, during surgery for a rare gyne cancer that was ER+.  I went into surgically induced menopause then, but have done very well without any HRT, only having some hot flashes. I've combatted any potential cardiac risk from lack of estrogen with exercise and diet, which has worked well for me thus far. 

However, like someone else mentioned, our bodies can continue to make estrogen through other means, and 9 yrs later, I was diagnosed with ER+ Breast Cancer.  I started Anastrozole last March, and was told that with it or Tamoxifen, the guidelines now recommend being on one of those meds for 10 yrs.  The reason I was given is because estrogen can be sneaky, and in some cases, can hide in cells, popping to the surface again around the 5 yr mark. 

I also stay away from as many Soy products as I can, but since it is in just about everything, that's nearly impossible.  Soy creates a type of phytoestrogen that mimics human estrogen, as does Flax. Wish I'd known that 10 yrs ago! The isoflavones and lechithins are the worst, and should be avoided when possible, but when unavoidable, like when shopping for bread or tuna, my oncologist and dietician both said to choose the brands that have the most natural soy in them, with the least amount of soy products and/or by-products on the label. Good luck with your decision. After talking to your doctor, like Suzanne suggested, and maybe even a genetic counselor, you should make the decision that feels the best for you, and then not look back.    

Subscribe with RSS
About Cancer Society

The content on this site is for informational purposes only. It is not a substitute for professional medical advice. Do not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Use of this online service is subject to the disclaimer and the terms and conditions.

Copyright 2000-2015 © Cancer Survivors Network