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A future weapon to combat mutated KRAS sounds promising

coloCan
Posts: 1849
Joined: Oct 2009
traci43's picture
traci43
Posts: 439
Joined: Jul 2007

Wow sounds promising.  I'm KRAS positive and hoping praying for new treatments!  This sounds good.  Hope they start trials soon.

tanstaafl's picture
tanstaafl
Posts: 969
Joined: Oct 2010

Essentially this paper supports the potential of stacking treatments until the combined treatment works.  

That's what we do with both chemo and supplements.   Natural molecules in treatment, whether pre-approved from on high before the FDA or a billion years evolution, appear more likely to "play nice" in aggregate to cover more bases, although it is not a guarantee and may take skill to stack high and effectively.   

devotion10's picture
devotion10
Posts: 642
Joined: Jan 2010

Your story is intriquing.

I know that you have spoken of your wife having surgery to combat her cancer and also she uses a number of supplements and immunotherapeutic agents ...

what types of conventional treatments has she had besides surgery?

Peace. ~ Cynthia

coloCan
Posts: 1849
Joined: Oct 2009

of interet to those with KRASmutation,

http://medicalxpress.com/print304174494.html

while 0thers who read this may want to find out more about ATT-11T,supposedly similar to irinotecan  but with less side effects)

coloCan
Posts: 1849
Joined: Oct 2009

which ended up being regurgitated so i'll exit the rut i dug with this German study on regorafenib,which is not too positive, as some here seem to have experienced

http://medicalxpress.com/print308569348.html

 

devotion10's picture
devotion10
Posts: 642
Joined: Jan 2010

I am really glad that you are posting this promising research. My husband had the KRAS mutation. While I am glad that he did not have to have treatments that would have been ineffective, I also found it distressing that he did not have as many treatment options that might have extended his life.

Peace. ~ Cynthia

coloCan
Posts: 1849
Joined: Oct 2009

mutation, a combo of Sorafenib and Irinotecan

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