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newly diagnosed with met uterine to liver and lungs any advice using carboplatin and gemcitabine

fnpanda
Posts: 2
Joined: Jan 2012

Has anyone heard of this combo and if so, how did it work for you?

Ro10's picture
Ro10
Posts: 1481
Joined: Jan 2009

Sorry to hear of your mets to your liver and lungs.  I have not had that combination.  I had 9 taxo/Carbo treatments and 10 taxol/ cisplatin treatments.  I wish you well with your treatments, and hope you do not have many side effects from it.  Sorry you have to join us on this. Journey.  In peace and caring.

fnpanda
Posts: 2
Joined: Jan 2012

I am very grateful for your welcoming response.  I've been dealing with uterine cancer since 2005 with internal radiation and surgery the first time, second it came back on the pelvic wall and now has mets to liver and lungs.  I am very torn between doing chemo and the small chance it would do anything and living my remaining life without any treatment.  The chemo wiped out 2 years of my life and made me very sick.  I don't know how to find out how much time I may have left.  Current pet scan showed hot spot on uterine wall, cancer on the surface of the liver, 2 nodes in one lung and 1 in the other.  I just lost my best friend to lung cancer and she passed in 9 weeks but two of her final weeks she was unresponsive.

ConnieSW's picture
ConnieSW
Posts: 623
Joined: Jun 2012

your cancer has progressed to this point.  I have not had a recurrence but often think about what I'll do if it happens.   I don't believe there is a right or wrong answer to your dilemma.  My chemo was the same as Ro's initial treatment.  I am not familiar with the second drug offered you but I'll be googling it (I'm a retired nurse so have a natural interest).  Are you confident in your medical team and their recommendations?  Do you feel you can talk frankly with them about your feelings?  How do your loved ones play into this?

 

Hopefully someone will show up soon with advice/dialog based on experience.  At any rate, please keep coming back.  We will try to help and, with all you've been through, you have much to offer us.  

 

take care

ccfighter
Posts: 399
Joined: Jan 2012

Hi, I am from the other gyn boards.  I have cervical cancer.  I initially had treatment of surgery, carbo/taxol, cisplatin with radiation and finished with two more carbo.  I had a recurrence about 6 months after I completed treatment with a tumor in lung and abdominal wall.  I had these resected and then started on carbo/gemzar.  I became allergic to the carbo and cisplatin so we tried oxaliplatin with gemzar.  After two infusions I was allergic to oxaliplatin as well.  My experience with the gemzar is that it was a lot easier to tolerate than the taxol.  You don't lose your hair.  Fatigue biggest complaint bu hard to know if it was really the gemzar or the platinum.  The carbo is the rougher of the two but compared to cisplatin and oxaliplatin easier to tolerate.  Gemzar spiked my liver enzymes but they returned to normal after treatment.  Carbo tanked my counts in Platlets and WBC but we are all familiar with that scenario.  Good luck.  In terms of quality of life I think the carbo/gemzar is easier.  Hugs.

HellieC's picture
HellieC
Posts: 459
Joined: Nov 2010

I'm so sorry to hear this news.  I am on treatment for my third recurrence.  First one was at vaginal vault - zapped with external radiotherapy and I was OK for 2.5 years.  Second recurrence on pelvic sidewall -  major debulking surgery followed by 6 cycles of carbo/taxol.  OK for 15 months.  Third recurrence on pelvic sidewall - no surgery due to location.  However this third recurrence is responding well to hormone therapy (aromatase inhibitor - letrozole) as my tumours are oestrogen receptive.  Perhaps hormone therapy might be an option for you to explore at this stage? My oncologist assures me that she has had ladies stay stable on hormone therapy for several years.  I do hope that it might be an option for you as it is a relatively easy treatment to tolerate and I have a good quality of life on it.
Kindest wishes
Helen

ConnieSW's picture
ConnieSW
Posts: 623
Joined: Jun 2012

Good to "hear your voice"

Goldheart
Posts: 36
Joined: Sep 2013

Hi HellieC, Can I ask how you take Letrozole. Pills or Capsules or injections? Apparenlty pilss are non-steroidail inhibitor and capsules or injections are chemo agents. Thanks Pav 

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