New Clinical trial for metastasis called Rigosertib

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nick770
nick770 Member Posts: 195
in Head and Neck Cancer #1

Hey guys, I wanted to let you know I started this phase 2 trial today. my latest scans showed that the tumors in my lungs had doubled in size in the last 3 months.

Rigosertib works by blocking cell division in cancer cells and causing them to die.

So  here is what I read "Six head and neck cancer patients included in this study had failed platinum-based therapies, and two of these patients showed a response to rigosertib—one with the disappearance of lung metastasis and another with greater than 50% decrease of liver metastasis. These two patients have received oral rigosertib treatment for 98 and 48 weeks" 

So 2 out of 6 had a good response but... Wow 98 weeks of chemo!! But if it's working. I suppose that is fine. 

 

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  • longtermsurvivor
    longtermsurvivor Member Posts: 1,842 Member
    #2
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    Hey Nick

    This is actually pretty neat stuff.  Appears this drug may be effective for both HPV + and HPV - Head and Neck cancers.  Here's an abstract:

    http://mct.aacrjournals.org/content/early/2013/07/23/1535-7163.MCT-13-0206.abstract

    Hoping you the best results.

     

    Pat

  • CivilMatt
    CivilMatt Member Posts: 4,722 Member
    #3
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    Oregon prayer warrior


     

    Good  Morning Nick,

    Sounds promising, I wish you the best of results.

    Best always,

    Matt

    I dig your big smile

     

  • katenorwood
    katenorwood Member Posts: 1,912
    #4
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    Hey Nick !

    Promising information !  I'll be keeping you in my thoughts !  Keep us posted on this trial.  Phase 2 means it's working for some.  And you will be one of them !  Hugs sent,  Katie

  • debbiejeanne
    debbiejeanne Member Posts: 3,102 Member
    #5
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    nick, i'm glad u found this

    nick, i'm glad u found this and i will b praying for it to work for you.  u r always n my thots and prayers.

    God bless,

    dj

  • jim and i
    jim and i Member Posts: 1,788 Member
    #6
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    Nick, sounds like it is woth

    Nick, sounds like it is woth a try. I am praying you are one of the successful ones.

    Debbie

  • phrannie51
    phrannie51 Member Posts: 4,716
    #7
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    Nick....

    This is wonderful news....maybe as far as chemo's go, this chemo isn't bad compared to the platinum chemos, huh?  Sending a ton of mojo and positive thoughts...

    p

  • nick770
    nick770 Member Posts: 195
    #8
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    phrannie51 said:

    Nick....

    This is wonderful news....maybe as far as chemo's go, this chemo isn't bad compared to the platinum chemos, huh?  Sending a ton of mojo and positive thoughts...

    p

    Yes, Phrannie According to

    Yes, Phrannie According to the paper I received most of what is disclosed is urilogical in nature...bleeding, pain, blockage...etc. So they advised me to drink lots & lots of water.

     i joking told my wife I need to get a urinal and mini fridge in our room Smile

     

    I will tell you if it had side effects like what 5FU and Taxotere did to me, I don't think I could handle 2 years

  • TracyLynn72
    TracyLynn72 Member Posts: 839
    #9
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    Sounds like

    it has good results!  Praying for you and wishing you the best!!

  • hwt
    hwt Member Posts: 2,328 Member
    #10
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    TracyLynn72 said:

    Sounds like

    it has good results!  Praying for you and wishing you the best!!

    Nick

    Glad you found a trial that sounds so promising...thanks for sharing. Prayers coming your way!

  • hawk711
    hawk711 Member Posts: 566
    #11
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    hwt said:

    Nick

    Glad you found a trial that sounds so promising...thanks for sharing. Prayers coming your way!

    Keep that attitude strong

    Nick

    You keep up the great attitude bud!  I believe this treatment will help you.   By the way, I'd like a urinal and fridge in my bedroom too, let me know how that conversation goes with your wife...lol

     

    all the Best

    Steve

  • Grandmax4
    Grandmax4 Member Posts: 723
    #12
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    I only want

    the best for you Nick, is the trial at The James? My Dr is Ricardo Carrau, I love this man and his team. Your smile is like a ray of bright sunshine~~take care, prayers that this works for you, keep us posted please

  • nick770
    nick770 Member Posts: 195
    #13
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    Grandmax4 said:

    I only want

    the best for you Nick, is the trial at The James? My Dr is Ricardo Carrau, I love this man and his team. Your smile is like a ray of bright sunshine~~take care, prayers that this works for you, keep us posted please

    Thanks for your compliment.
    i

    Thanks for your compliment.

    i started a page on FB about the drug. I hope to find otheres who have been on it.

    Yep, They are at the James, Actually it's in a pill form, but I have to go in once a week for a check up. So if anyone wants to grab lunch (or some form of it, ya know what I mean) I'm there on Fridays

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