Aug 28, 2013 - 4:27 pm
Has anyone had their AFP elevate after returning to normal post resection?
My husband had a 1.9 x 1 x 1.1 lesion removed from the left lobe of the liver. The pathology showed focal vascular invasion but the surgeon expected that it was completely curative. AFP returned to normal 1 week post resection
At our three month check up post resection, MRI of the abdomen came back fine, CT of the chest came back fine but AFP was elevated to 191. Oncologist had us return next day for a Pelvic MRI and another AFP. Next day she reported that the Pelvic MRI came back normal but AFP was now 212. The following week a PET scan was done and the PET scan only showed a very dim light up near the surgical site. Radiologist nicknamed "Eagle Eye" performed the ultrasound himself and did not see any su****ious activity where the PET scan indicated.
A week later we saw the Transplant surgeon that performed the resection. He had a lipiodol angiography ordered and he ran the AFP again. It was now elevated to 505.
The following week the angiography was done and it came back inconclusive. A week later they repeated the CT to look for remaining lipiodol which would indicate where the cancer was and it came back inconclusive again.
Back to the oncologist yesterday. She suggests waiting and repeating CT in 30 days. She stated that she believes there is HCC recurrence but they cannot find it. AFP yesterday was 897.
So to recap - AFP has elevated to 897 in 30 days. Abdomen MRI, Chest CT, Pelvic MRI, PET scan, liver ultrasound and two CT's of liver only have been performed in the last 30 days and cancer cannot be found. All of the doctors are telling me this is a rare occurrence. Doctor is recommending Y90 therasphere to the left lobe even though they cannot find a tumor.
Has this happened to anyone else out there? I cannot find anything and I mean anything regarding this scenario. BTW we are being treated at Northwestern Memorial in Chicago. Have an appt with Mayo scheduled October 24.