Apr 10, 2013 - 3:01 pm
I am from the gyn boards. I have metastatic and recurrent cervical cancer. I had debulking in December to remove a lung nodule and a tumor on the abdominal wall that had attached to a small bowel loop which was also resected. Started chemo again in Feb. with carbo/gemzar. Counts tanked, Platlets to 30 and WBC 1. So we decided to switch to cisplatin and then I had an allergic reaction with hives and everything. Tried it again with premeds and had another reaction so that is out. I had a molecular profile done of my recurrent tumor and it indicates that it should be platinum sensitive with little benefit of any other chemo options. So, in order to try to get some platinum into my body, tomorrow we will be trying oxaliplatin. I will get this every two weeks with gemzar.
My question is what should I expect from this Oxaliplatin. I have read through some old posts here and the chemo care website. What exactly is this sensitivity to cold like? How long does it last. Is this side effect dose dependant? Does it worsen?
Nausea? Is this well controlled with Zofran and Compazine or do you need heavier Emend type meds? I am very familiar with Platinum chemo, I did 6 Carboplatin and 5 Cisplatin at my original diagnosis so if anybody can make a comparison to those chemos that would be helpful.
What is the infusion like? Any immediate reactions?
Has anyone here every had an allergic reaction to another platinum drug before? If so, did you try another platinum and you were ok or did you continue to have reactions to platinum chemos?
Having allergic reactions to chemo is scary and I am really nervous about trying another one. I will premed with prednisone and they may give me benadryl as a precaution also. Just want to have this be over with. The weather is turning beautiful and all this chemo is cramping my style. And, I am not quite prepared to die of an anaphylactic reaction when I have no evidence of disease based on March CT scan. Thanks.