Mar 11, 2013 - 5:30 am
Please don't read this if life style interventions will cause you stress.
Please read this if you are interested in life style interventions with regards to diet.
Its a strange co-incidence that this article landed in my inbox the same day as my increased cancer marker, I am a making plans to do the full ketogenic diet, sold by doctor COY. its the ultra marathon of life style interventions. On a separate thread re a book review, the premise of the books was attacked and indirectly the lifes work of many worthwhile doctors. I presonally know one of the doctors and am impressed generally with their knowledge ( a few things on colorectal i think they are missing ). basically this discussion is focused on diet and the current science.
PS the diet, and fasting well its a low cost, effective strategy to try, of course discuss with your doctor. ask them about tktl1. they won't know, you will need to educate them each step of the way.
By Dr. Mercola
This quote is one of many from the book below, DER is dietary energy restriction. If you are interested, just google ketogenic and cancer, some links are on my blog.
Late-onset DER also delayed malignant progression and significantly extended mouse survival. These effects were associated with changes in metabolic biomarkers, including blood glucose and lactate levels (Fig. 17.15). We showed that expression of these biomarkers was linked to the downregulation of the IGF-I/ Akt/ Hif-1α signaling pathway . Our findings emphasize an important role for activation of the IGF-I/ Akt/ Hif-1α signaling pathway in potentiating the antiapoptotic phenotype of astrocytomas and indicate that DER targets this signaling pathway. A goal of the cancer drug industry is to target the IGF-I/ Akt/ Hif-1α pathway for tumor management. Our results show that DER can target this pathway without the use of expensive and toxic cancer drugs. Cancer patients and their oncologists should know about this.
Seyfried, Thomas (2012-05-18). Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer (Kindle Locations 8206-8213). John Wiley and Sons. Kindle Edition.