Dec 25, 2012 - 6:06 pm
Dear members - I am new to this community and am seeking your input for understanding the treatment regimen for a relapsed B cell (aggressive) or marginal zoneNHL (MZL/indolent). My mother (age 56y)was diagnosed with B-cell NHL in March 2011. She finished 6 rounds of R-CHOP followed by radiation therapy (30 rounds) and was declared in remission/cured late 2011. However the most recent PET (June 2012 was-ve and Dec 2012 was +ve) showed she has a relapse. At this point, the Oncs are unclear (as more tests are being done) to determine which type of relapse is it. Based on my limited knowledge - I have a few questions and I wanted to seek the community's input on the same.
1. The onc mentioned MiB1 rate? Less than or equal to 38% indicates indolent. My mothers is on the border and so they are no clear whether it is indolent or aggressive
2. Another ONC suggested R-ICE followed by ASCT - we want to keep that as our last option - but I need to know other possible chemo/Rituximab or similar options before it comes to ASCT.
3. Upon a second opinion, the ONC suggested Treanda + R - not sure how patients have reacted to this and the overall success rate...
At this point I wanted to know from the community with relapse NHL either B-cell or indolent MZL - what are the typical treatment options your ONC advised and you received.