Nov 14, 2012 - 6:19 pm
Hello wise people
My mom has colon cancer stage 4, with mets to liver and lungs. No surgeries. Ca 20 tumors in liver, largest ones measuring 5 cm. At the time of diagnosis in Nov. 2011 she started Folfox. 4 month break, then Folfiri in Oct. 2012. No Avastin due to family history of blood cloths.
We've just been told she has K-RAS (and BRAS?) mutation, so she can't have the third line treatment of Cetuximab/Erbitux or Pantumumbab/Vectibix. The doctors said her only options now are Folfox and Folfiri.
I was so sure there were other treatments than Folfox or Folfiri, even with KRAS-mutation?
My worry is that there are in fact working drugs, but that they are not available or offered in my country. The doctors even said flat out (the time they denied us Neulasta) that the US health care system often offered better treatments, for those who could pay of course. Yes, we are thankful for our free healthcare here, but sad if it limits our options!
My mom is terrified at the thought of Folfox again due to the neuropathy. With only two possible treatments, I am worried for her body becoming immune to them. I was hoping for more alternatives.
Am I right in taking this all as bad news? Can anyone enlighten me a little? :)