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Blocked portal vein

Dannielle
Posts: 11
Joined: Sep 2012

Has anybody who has liver cancer or known anyone with liver cancer who had a blocked portal vein? My dad is going on Nexavar and we were wondering if it will shrink it. Any info will be helpful. Thank you!

XtremediverHCC
Posts: 57
Joined: Feb 2011

I had a Portal Vein Thrombosis following my last recurrence of HCC. It was treated by Warafin pills and blood was drawn every week or two to check on my blood counts. It was 15cm and eventually it dissipated and has not returned. Don't know if Nexavar itself will help, however.

Suzieste
Posts: 3
Joined: May 2012

Hi my dad have liver cancer,from HVB and portal vein thrombosis he is on nexavar we had ablation he was ok and now the doctors are saying that the thrombosis is bigger and they can't do anything.please tell me why with the Warafin thinners did you have good results??because no one doctor suggest that.thank you

XtremediverHCC
Posts: 57
Joined: Feb 2011

Suzieste, I honestly do not have any idea why Warafin was prescribed for my thrombosis and why it worked so well on me. I had RFA 2 years after resection surgery. My HCC occurred following my clearing the Hep-C virus through treatment by the same doctor who treated my Cancers. Portal Vein Thrombosis is blood clotting inside the vein; it is not cancer per se. If your father has a Portal Vein Tumor, that is different and may be why your doctors aren't mentioning treatment with Warafin. Warafin is merely a blood thinner and the Portal Vein supplies 75% of the blood through the liver. I hope this helps and will clarify any questions you might have. Good luck and make sure you get the doctors to explain exactly what is happening with you father.

Suzieste
Posts: 3
Joined: May 2012

Thank you so much!

mydeardad
Posts: 7
Joined: Aug 2012

My father has stage IV liver cancer with a tumor in the portal vein. He has taken Nexavar and had Thermo-spheres implanted. From what I understand, Nexavar will not shrink the existing tumors. It is supposed to stop new growth. It is the radiation from the Thermo-spheres that will shrink the tumor.

The nexavar was too much for his body, even though he was only taking half of the recommended dose. We see his oncologist this Friday and hopefully his counts are well enough that the chemo can be restarted.

mydeardad
Posts: 7
Joined: Aug 2012

My father has stage IV liver cancer with a tumor in the portal vein. He has taken Nexavar and had Thermo-spheres implanted. From what I understand, Nexavar will not shrink the existing tumors. It is supposed to stop new growth. It is the radiation from the Thermo-spheres that will shrink the tumor.

The nexavar was too much for his body, even though he was only taking half of the recommended dose. We see his oncologist this Friday and hopefully his counts are well enough that the chemo can be restarted.

bluequail
Posts: 1
Joined: Oct 2012

Since we are already into October, I hope your dad's oncologist had some good news for him.

Back in 11/07, my dad was diagnosed with advanced liver cancer. He was given 3 months by his doctors. At that time, we were told that his largest tumor was 11cm X 7cm, and that there were numerous satellite tumors.

The very day that Nexavar was pulled from clinical trials early (because it was showing to be so successful), the doctor wrote a prescription for my dad for it. My dad was started on it, and even though it didn't shrink the growth of the largest tumor, it did stop any more growth of it. Unfortunately, even more satellite tumors started growing.

He ended up having a combination of the Nexavar and TACE treatments. That was back in 2008 and he is still alive today, in 2012.

But that year that he was originally diagnosed, in February (2007) he had had a CT scan done to see if he was able to start treatment for Hep C, and there were no growths at that time. By 11/07, that largest tumor was eleven centimeters by 7 centimeters.

The hospital that oversaw his treatment was University of NM hospital on Lomas Blvd. in Albuquerque.

I hope this information helps you or anyone at some level.

LISAmaried
Posts: 6
Joined: Aug 2012

My father just received the results of his first PET scan after his therasphere treatment, unbeleivably, 60% of the tumor is now dead and shrinking. His cancer center told him it is the best response they have ever seen. I have been trying to find information on quality of life and life expectancy after therashphere, but it is very hard to find this info. Maybe because of the relative newness off the treatment? All I know is your post has made me very happy. My dad had a 8.5cm tumor, and no other liver disease. I knew the fact cancer is the only disease he is fighting helps his odds, but to know your dad has lived for five years, puts me over the moon. Dad has been so positive all along, telling me and my step mom that he just KNOWs he will beat this. I am an only child and I learned that he had liver cancer 12 hours before I found out my mom has lung cancer, so I have really needed some kind of hope to hold onto. His news yesterday and finding your post today is it. I knew miracles can happen, I am praying we are receiving one. The best news is he is coming to visit with me and his grandchildren for Thanksgiving. I cannot wait to give him that hug!!Bless you for sharing your information.

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