Aug 05, 2012 - 2:09 am
I was recently diagnosed with Stage III CKD (chronic kidney disease). I have no known risk factors i.e. high blood pressure, high cholesterol, overweight, family history, race, etc. except my age,74. I've been pondering this and wondered if it could be related to my ovarian cancer treatment almost 17 years ago. I had 6 treatments with taxol and cisplatin. The last three were also administered through the abdomen (paritoneally). I finally googled kidney disease and cisplatin and on the National Cancer Library I found the following:
"Kidney disease is a common side effect of cisplatin. The risk of this side effect increases with higher doses and the longer you are treated with the drug. Your healthcare provider will give you fluids before your treatment and may ask you to drink extra fluids after your treatment to protect your kidneys."
I guess that answers that. Now my question is: Is it likely to remain constant or continue to worsen? I've kept my blood reports for many years and it appears that the GFR was not part of a routine blood test until about 10-12 years ago. My GFR, Bun Creatinine ratio have been relatively constant (GFR around 42). I'm grateful I survived the ovarian cancer with no recurrences but would like more information. I presume the company that manufactures cisplatin would be mum on the question because of liability issues. Anyone have the same issue?