Aug 02, 2012 - 7:31 pm
First I would like to offer some encouragement to those recent entries with Gleason 9 level prostate cancer. I am currently 58 and was diagnosed in March, 2008 with prostate cancer- PSA 29.7, Gleason 9 (4+5), with the biopsies on the left side of the prostate involving between 50% to 100% of tissue. After receiving eight weeks of IMRT radiation (73.8GY) and subsequent 3 years of hormone therapy (July,2008 to July,2011 - and still responding) my PSA came to it's lowest at 0.21 (April,2011). Since that time, I have been off hormones with my PSA rising back to 2.04 (July, 2012).
Life has been good - enjoying the family (still chasing the wife around), playing golf, some fishing with my boy, and yes - even enjoying work! Particularly enjoyable has been bringing into the world two new grandchildren. Hang in there...
My question I would like to ask everyone, though, is about interpreting nadir criteria. The standard rule of nadir being (+2.0) above minimum comes from radiologists. It is not based upon a combination of radiation in combination with hormonal therapy. My radiologist has suggested that correlating testosterone levels along with a rising PSA and establishing a PSA velocity and doubling time will be needed to verify what is happening. Should I be more preemtive or simply wait until my next scheduled appointment (November)??
Your thoughts/suggestions are appreciated.