I am usually at the gyn cancer boards as I am a cervical cancer patient, but am over here on prostate in hope to gain a little insight on prostate cancer treatment. A friend of mine is battling stage IV prostate cancer. He was diagnosed about two years ago after falling down in his yard while mowing the grass and not being able to move his legs. He was taken via ambulance to the hospital where it was determined he had a tumor on his spine. This was a metastasis from prostate. After more testing there was also a small tumor apparent in his lung. He had been under the care of a cardiologist who checked his PSA regularly and ignored the irradic PSA level test results. Mistake. Big one. My friend is in his late 50's.
At the discovery of his spinal tumor he underwent three weeks of targeted radiaiton to the spinal tumor which allowed him to regain the use of his legs. He then started hormone therapy to induce chemical castration. All was stable for about a year until his tumors began to grow again. His oncologist decided it was time to start chemotherapy. He completed four rounds of docetaxol and taxotere but still the tumors persisted. A met to his femur required more radiation to ease pain and allow mobility. Just recently he was entered into a phase 1b clinical trial with a drug called C90 as well he is taking zytiga.
After the initiation of the clinical trial, the c90 caused a terrible rash that encompasses most of his body. He has been put on steroids and antibiotics to prevent infection in the rash. He is contemplating not continuing with the trial.
My question to you all here on the board, are you aware of this clinical trial? Does anyone here have any experience with it? Also, are there other treatments available for hormone resistant prostate cancer that he has not been offered? Any information would be greatly appreciated. Thanks.