I just joined this network and am wondering if anyone has any insight or experience with Gemzar chemotherapy and whether it works on abdominal fluid build up.
My mom was diagnosed with advanced primary peritoneal/ovarian cancer 10/08. She initially had fluid build up in abdomen and around lungs, which is how she was diagnosed. She had paracentesis at the time to drain the fluid, but the chemo she was started on at the time(Taxol/Carboplatin) took care of the fluid. She had an excellent initial response, and after undergoing chemo, surgery, chemo again and then Intra-abdominal port chemo, she was cancer free for almost a year. Disease came back in mid to late 2009. Since then she has been on Doxil, Taxol again, and most recently Topotecan. She took a break from chemo for several months as the disease was minimized in her stomach/abdomen. A few months back, she had a great deal of fluid buildup, and scan showed growing disease. This is when she was started on Topotecan, but despite this therapy, has had to have 5 paracenteses, draining 3 liters a fluid approx every 2 weeks. Her doc seems to be remaining positive, but obviously we are concerned! She started on Gemzar this past Friday. We have been told Gemzar is similar to Topotecan ( a little slower working and gentler on the system). Has anyone had similar sx, experiece with this fluid buildup or with Gemzar as a drug? Thanks for any help!