Feb 28, 2012 - 6:28 pm
I met with my primary gyn-onc today re being more aggressive with chemo for my UPSC disease progression. He will not equate 'aggressive' with 'effective'. He is not on board with doing a carbo/taxol treatment (as recommended by second opinion gyn-onc)as he believes negative toxicities far out weigh potential benefits. He would do single agent carbo if I am not comfortable with doing my current, conservative, tamoxifen therapy. I do love the no side effects part of this!
However, he is PI for a clinical trial opening in a few days that is specifically for recurrent endometrial cancer. Since other treatments are really just adopted from ovarian cancer treatments, one that is for my cancer may be worth giving it a shot. I can always leave the trial and go with carbo or back to tamoxifen if I have concerns. Also, there will be careful monitoring with scans every 8 weeks. I will be randomly assigned to either oral daily tabs or weekly IV infusions. There is no standard care arm, all participants will receive investigative drug.