Jan 05, 2012 - 7:00 pm
Hi everyone! I wanted to ask if anyone else found that their original biopsy and later the tissues removed during surgery contained completely different kinds of uterine cancer?
My original biopsy showed endometroid cancer with clear cell features and was classified high-grade. But the surgery revealed no clear cell in the uterus, only Grade 1 Endometroid.
Surgery showed the cancer to be only in the lower uterine segment with a focal cervical stromal invasion, so it was labelled stage 2. But myometrial invasion was only 10-20 %. .
The doctors are nervous about this microscopic bit of tissue containing clear cell features or "clear cell change" and are treating the cancer as if the whole uterus was clear cell -- just to get the "bad guy," as my primary doctor put it.
I am scheduled to have chemotherapy (6 cycles of Carboplatin/taxol as well as brachytherapy).
Still, I am puzzled as to how the original biopsy -- just a small piece of tissue the gynecologist happened to get when he took a sample of the uterine lining. He did not aim for a visible polyp or anything, he told me -- could contain clear cell features when there is not a single cell of this to be found in the whole uterus during the surgery (radical hysterectomy with lymph nodes etc)
If any one has had a similar experience, please share.