Sep 23, 2011 - 12:48 pm
I have been in chemically induced menopause since my first chemo but had one bout of very light bleeding in January. Since then, I had a uterine biopsy (possibly one of the most painful experiences of my life and have given birth twice). The biopsy came back normal. I have been getting internal ultrasounds every 8-12 weeks and we have been watching cysts grow on one of my ovaries and my uterus has thickened. I am now scheduled to have the cyst, and probably the ovary removed and a thorough D&C.
Throughout my chemo, I got almost every little known side effect from the drugs I was taking. My oncologist had to look up some symptoms to see if they were related to treatment as she hadn't seen them before and they were all listed as unusual but possible side effects. Therefore I am really nervous that I am falling into the lesser category of people who get other cancers from tamoxifen.
My oncologist will not put me on aromatase inhibitors because she doesn't believe I am truly in menopause. My gyno does not want to remove my "lady parts" as she is concerned about long term side effects on my heart from doing so, even though that would allow me to switch off tamoxifen.
Nobody is willing to perform a CYP2D6 as my insurance won't cover it and I cannot afford to pay for it out of pocket. It would be nice to know that I at least have a chance of the tamoxifen working if I'm going to face all these side effects and worries.
Anyway, sorry for the long-winded post. I'm just wondering when the risks from the tamoxifen actually outweigh the possible benefits of it for people, though I am worried I am asking this question too late.
Also, what have others been told about having all thier "lady parts" removed and possible issues down the road from it? My gyno said that it has been shown to cause increased risk of heart disease if done before the age of 63 and I am now 45. It seems to me that those risks might be moderated by being able to shift off the tamoxifen to a drug that is less likely to spike my triglycerides...or that one might simply balance out the other and at least I would no longer have to worry about uterine/ovarian cancer from the tamoxifen, if I don't have to worry about that already.