I was wondering if anyone has taken xgeva in combination w/firmagon. My dad has advanced pca with extensive bone mets. He had 1 shot of lupron in march then was switched to firmagon to avoid the tumor flare from Lupron. He had his second shot of firmagon and second xgeva shot 13 days ago, he had severe nausea today and actually vomited. He's also very tired and is experiencing serious hot flashes. His robe was drenched! Has anyone experienced these side effects from either firmagon or xgeva? Also his psa was 200 in march then went down to 45 in April after Lupron but then went to 65 after one firmagon shot. The dr said not to worry he will check it again in 2 weeks to see what's going on. So to date he's had 1 Lupron 2 firmagon and 2 xgeva. He'll get his third firmagon/xgeva on june 18th. Yesterday he was also having pain in his bones but feels better today. Please any information is helpful! Three days ago he said he was feeling amazing! Not sure what's happening now. Thanks so much!