Jan 07, 2011 - 11:45 am
Just had a follow-up for my husband's RCC (undefined with translocation 11.2xp) and found lymph node growth and spread to lung & stomach. We think that he is starting to become resistant to Sutent. I have read in many articles and message boards that on average this seems to happen after about 12 months of treatment. He's been on Sutent since April/May 2010. Just wondering if there is anyone else out there that has experienced Sutent resistance. How long were you on Sutent? Was it is your 1st line defense treatment after nephrectomy? How did you find out? Looking back, were there any warning signs that Sutent was starting to fail (increase in side effects compared to previous cycles, increased pain)? What was the next step with your doctor (more scans, changed prescribtion, etc)? What treatment did you start after Sutent failed? Was it successful and for how long? What are the side effects while on the second line treatment?