Clinical Trial AMG 386 and Doxil

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Nat671
Nat671 Member Posts: 9
edited March 2014 in Ovarian Cancer #1
Hi Everyone,
my name is Natalie and I'm knew to this site. I was wondering if anyone has had experience with the clinical drug AMG 386 and Doxil. I'm starting with these treatments next month and I really don't know what to expect. Thanks in advance for any helpful advice or insite to this matter.

Nat671

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  • kikiz
    kikiz Member Posts: 94
    #2
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    Sorry to that you have to be
    Sorry to that you have to be here but welcome. I don't know anything about them but I am sure someone will be able to help you. You have found a great resource here. Wish you the best and will keep you in my prayers.

    Lori
  • Nat671
    Nat671 Member Posts: 9
    #3
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    kikiz said:

    Sorry to that you have to be
    Sorry to that you have to be here but welcome. I don't know anything about them but I am sure someone will be able to help you. You have found a great resource here. Wish you the best and will keep you in my prayers.

    Lori

    KiKiZ
    Thanks so much. I hope to get some feedback, because I'm really scared about undergoing this yet again.

    Nat671
  • Hissy_Fitz
    Hissy_Fitz Member Posts: 1,834
    #4
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    Nat671 said:

    KiKiZ
    Thanks so much. I hope to get some feedback, because I'm really scared about undergoing this yet again.

    Nat671

    I did a brief bit of
    I did a brief bit of research on the study and there isn't a lot of data, since it is Phase Ib. At least it's not a blind, two-arm study, so you know going in that you will be getting the "real thing". I think clinical trials are the way to go, if you qualify for one like this. You will be watched carefully for side effects, etc.

    A woman in my local support group was part of the clinical trial when Taxol/Carboplatin were being tested for ovarian cancer. She was Stage IIIc and that was over 10 years ago. She has never had a recurrence.

    Carlene
  • nancy591
    nancy591 Member Posts: 1,027 Member
    #5
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    Hi Nat
    I have no informtion on the trial you mentioned but I will be starting a trial myself next. I will start on ENMD2076.

    Good luck and I love your profile pic!
  • Mwee
    Mwee Member Posts: 1,338
    #6
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    Welcome Natalie
    I don't have experience with the clinical drug, but I had four rounds of Doxil this summer. Doxil is fairly easy to tolerate, but you have to watch out for the side effects called hand and foot syndrome. You will receive instructions, but basically you should ice your feet and hands during and after infusions, avoid citrus for five days, take cool rather hot showers and use lots of hand cream on those feet and hands. Let me know if you need more help with this, ok?
    (((HUGS))) Maria
  • Nat671
    Nat671 Member Posts: 9
    #7
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    Mwee said:

    Welcome Natalie
    I don't have experience with the clinical drug, but I had four rounds of Doxil this summer. Doxil is fairly easy to tolerate, but you have to watch out for the side effects called hand and foot syndrome. You will receive instructions, but basically you should ice your feet and hands during and after infusions, avoid citrus for five days, take cool rather hot showers and use lots of hand cream on those feet and hands. Let me know if you need more help with this, ok?
    (((HUGS))) Maria

    Thanks Everyone!
    @ MWEE..I
    Thanks Everyone!
    @ MWEE..I had the hands and foot syndrome when I was on Taxol/Carboplatin. It drove me crazy. But I will follow your advice.
  • zenisthou
    zenisthou Member Posts: 26
    #8
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    My doctor suggest Doxil with AMG386 too
    Dear Nat, How are you doing? Can you share your experience on the Doxil + AMG386 treatment with me? My doctor suggest me to get the treatment for recurrent Ovarian Cancer.
    Thank you, and best wishes to you

    Tracy

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