Trial did not work

luv3jay
luv3jay Member Posts: 533 Member
edited March 2014 in Colorectal Cancer #1
Just wanted to let everyone know that I didn't have success with the TMZ/ABT 888 trial. Although the liver mets remained stable, there was a little growth in some of the lung mets. However, he does have several patients on this trial that have had good success. And I think that overall, this combo was not a total failure because most of the mets remained stable. Anyway, my onc doesn't want to risk having me continue on this combo for now. We aren't behind the 8 ball yet, so we're going to try to come up with something different while we're still in control. I'll keep you guys updated and thanks for all your well wishes.

-Sheri

Comments

  • AnneCan
    AnneCan Member Posts: 3,673 Member
    #2
    Sheri
    I am sorry this trial didn't work better, but you are right - it wasn't a failure either. Thanks for letting us know + please keep us updated.
  • lisa42
    lisa42 Member Posts: 3,625 Member
    #3
    don't get discouraged
    Hi Sheri,

    Thanks for sharing your recent news with us. I've wondering about how you're doing!
    As you said, it wasn't a total failure, since many mets remained stable. Who knows what might have happened if you had been on no treatment at all during this time.
    Let us know what treatment you decide on next.
    Take care!!

    Lisa
  • Unknown
    Unknown
    #4
    lisa42 said:

    don't get discouraged
    Hi Sheri,

    Thanks for sharing your recent news with us. I've wondering about how you're doing!
    As you said, it wasn't a total failure, since many mets remained stable. Who knows what might have happened if you had been on no treatment at all during this time.
    Let us know what treatment you decide on next.
    Take care!!

    Lisa

    This comment has been removed by the Moderator
  • dorookie
    dorookie Member Posts: 1,731 Member
    #5
    Keep Fighting, Sheri
    I am sorry that trial didnt work, but there will be others, and I pray that they will work. I am so glad that your ONC seems to have a plan. Sounds like you have a great medical team with you.

    Sending prayers up for you...stay strong...

    HUGS
    Beth
  • geotina
    geotina Member Posts: 2,111 Member
    #6
    Sheri
    I'm sorry you are having such difficulties. I was not aware you were doing clinical trials. I'm sorry. I follow your story and knew you had experienced a recurrence and had not seen you post in a while and was wondering what was going with you.

    I think of you often. I wish you the best in keeping the cancer under control and look forward to reading that the next treatment option is working better for you.

    Best Wishes - Tina
  • sheri22
    sheri22 Member Posts: 273
    #7
    SORRY TRAL DIDNT WORKI
    Sheri sorry the trial didnt work for you sounds like your dr is pretty aggressive in helping you fight this beast take care keep up the good attitude

    Sheri22
  • tabur
    tabur Member Posts: 71
    #8
    Hi Sheri
    Sorry the trial didn't have better results. Are you still at GUH? We went there expecting a trial that included ABT-888 but that particular trial wasn't succeeding so well either. We were just at GUH on July 16th when Pam had her second TACE treatment. The first treatment appears to have shrunk the tumor he went after. The second treatment targeted the largest tumor. We have a PET/CT scheduled for August 31st to see the results. We are glad to hear most of your mets remained stable.

    Al
  • pluckey
    pluckey Member Posts: 484 Member
    #9
    Sheri,
    I am so sorry about
    Sheri,

    I am so sorry about these results but am glad liver mets are stable. What other procedures have you done? anything else available to you that you might consider? cyberknife, sir spheres, hai pump???

    (hugs) to you

    Peggy
  • tootsie1
    tootsie1 Member Posts: 5,044 Member
    #10
    Praying
    Hey, Sheri.

    I'm praying the right "something different" will come along soon and make a huge difference for you.

    *hugs*
    Gail
  • mom_2_3
    mom_2_3 Member Posts: 953 Member
    #11
    Sheri
    Sheri,

    I am sorry that the trial didn't have the perfect drug combination, however, stable is great news. I hope you find the perfect plan soon and as always, you are in my thoughts.

    Amy

    PS As Pluckey mentioned, have you considered other surgical options?

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