So glad to have found this board with real people and their stories. I have been attached to my pc for information since my diaagnosis on May 19.
I had no prior symptons and had never even heard of anal cancer before. I went for a routine colonoscopy ( my first one) on Feb 22, 2010. There wew two polyps removed one in the ascending colon and one in the rectum both benign appearing. The 4mm polyp in the rectum came back as fragments of condyloma with severe dysplasia/carcinoma in-situ with a positive for hpv-16. I had no idea what hpv-16 was so I did some research and saw that it was sexually transmitted, could be caused by genital warts, or prior uterine cancer.
I did have endometrial cancer in 2000 stage 1a with no nodal involvement and no further treatement after having it removed via hysterectomy. I have also been married for 27 years. I am 58.
My gastro doctor suggested hat I see a surgeon to have it removed as it could become cancerous. I went to see a prominent surgeon that specialises in surgery of the rectum and he examined me and scheduled for a sigmoidoscopy as an outpatient in the hospital. The surgery was to no avail as he did not see anything to remove. He had me scheduled for six weeks followup in his office for a rectal exam. When he examined me this time he did feel a rough area right inside the anal canal at the anal dentale line. He biopsied this and it came back from the path report as in situ squamous cell carcinoma. So agaim outpatient surgery was scheduled for May 19. which resulted in the mass being removed via local trans anal disc excision at the anal rectal junction. The results were squamous cell carcinoma in situ with a focal early invasive component and the staging as T1 Nx Mx. The histoloc grage was G2 with the tumor invades submucosa.
The surgeon suggesred a consultation with a radiologist because of the early invasive component he said so i went to see him. He concloded that I have early stage 1 anal cancer. He was on the fence as to how aggreesive to proceed and he said that he was going to present my case to the cancer tumor board that he meets with weekly to discuss different cancer subjects.
The general concensus was that I have radiation combined with one chemo drug 5fu and he referred me to the oncologist. At this meeting the oncologist said that he would like to administer a single 5fu (2000 units or whatever the measuements is called) drug interveinously weekly instead of the usual protocol of the 96 hour infusion in the first and last week and with no mitomycin. This being given over an 8 week period concurrently with the radation which I think is a 6-7 week program.
Sorry this is so long but I am concerned, does anyone have any experience with this? They tell me my case is very rare and so early that they dont want to overkill. Everything I have read suggest the radation combined with the two chemo drugs.
Mu other concern is that i do have another opinion appointment with The Moffit Cancer center in Tampa but cannot get an appt until July 16. I am starting chemo on Tues. June 8 and radiation thereafter next week. Will that appointment be too late?
Thanks for reading this long post.