Mar 10, 2010 - 5:04 pm
New research out last month that I just saw today:
Pelvic and Para-aortic Lymph Node Removal in Endometrial Cancer
In women with endometrial cancer who are at medium to high risk for recurrence, removing both the pelvic lymph nodes and the para-aortic lymph nodes reduces mortality by 52% over that for women who have just the pelvic lymph nodes removed. Japanese researchers studied 671 women with endometrial cancer and specifically analyzed outcomes among 328 women at medium to high risk for recurrence. These women also received radiotherapy or chemotherapy. Treatment with chemotherapy alone reduced mortality by 41%, independent of the effect of lymph node removal on mortality. Combined lymph node removal did not improve survival among women at low recurrence risk. The study was conducted at the Hokkaido University Graduate School of Medicine in Sapporo, Japan. The researchers thus recommended removal of pelvic plus para-aortic lymph nodes in the treatment of patients with endometrial cancer who are identified as being at medium to high risk of recurrence. The study results were published in the February 24 online issue of The Lancet.