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DCIS and herceptin



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terri805

				          
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        			    February 9, 2010 - 1:49am			  			

			
			
Has anyone on this site participated in the research study of dcis dx and taking herceptin? My dr asked me if I wanted to participate in the study and I don't know if I do or not since I won't know if I am given a placebo or herceptin until after the study is completed.It is a 50/50 chance of being chosen to take it and what about the side effects?


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tommaseena's picture
						
tommaseena

				      
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February 9, 2010 - 5:31am

			
Herceptin
			
Herceptin targets the HER2 neu gene so if you are not HER2+ then I don't know why they would give you Herceptin.


Margo



			
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Sher43009

				      
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February 9, 2010 - 7:45am

			
If you are HER2+ I would not
			
If you are HER2+ I would not do the study. The herceptin blocks the HER2 receptors keeping the cancer from coming back. I am HER2+ and would not take the chance of not getting the Herceptin.



			
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terri805

				      
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February 9, 2010 - 10:59am

			
HER2+
			
They have not tested my tissue removed from the lumpectomy for HER yet and I guess they normally don't for DCIS. The dr said if I wanted to participate in the study they would send the tissue for testing to see if I would be a candidate for herceptin.I think I am leaning toward not participating in the study and just going with the radiaton and arimidex.



			
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Kat11

				      
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February 9, 2010 - 8:16pm

			
Could there be a study to
			
Could there be a study to see if herceptin might help other forms of breast cancer besides the her2 pos.



			
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canoegirl

				      
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February 9, 2010 - 9:58pm

			
Why not try it
			
I read a report recently that stated that most DCIS is HER2 Pos.  They didn't know why when it spreads to IDC that only 25-30% are postive.  If Herceptin could cut down on the number of DCIS that spreads beyond the ducts it would be great.  Of course I haven't started Herceptin yet, so I don't know how bad the side effects are.  If it's miserable, you might not want to do it.   Just food for thought.  Good luck with whatever decision you make.  Can you get the pros and cons from your doctor?



			
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