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Thyrogen and fertility

BTrue06
Posts: 3
Joined: Sep 2006

Does anyone know if there is any problem with Thyrogen effecting ones future ability to have kids. I was reading the pamplet in my Thyrogen kit and it said, under pregnancy, that the effects on fertility have not been tested. I don't mind going Hypo this time around if there is any risk. does anyone know? Thanks

Rustifox's picture
Rustifox
Posts: 131
Joined: Mar 2005

Thyrogen has not been tested in pregnancy and/or fertility issues, however, if treatment with radioactive iodine is being considered - I131 - there are implications from the treatment doses of that.

In general, treatment doses of I-131 can cause some temporary issues on fertility - temporary ovarian failure, but it is also recommended that we do not consider becoming pregnant for at least 6 months to a year following treatments, either. Here is some info about that issue:
http://pmj.bmj.com/cgi/content/full/78/916/92
and this one states:
"Temporary ovarian failure has been described in about 25% of treated females, however, this may be related to other factors such as hypothyroidism...":
http://www.indyrad.iupui.edu/public/lectures/HTML/NM/thyroid/THY10.HTM

Thyrogen (also search under 'alfa thyrotropin', the generic name) is a fairly 'new' drug, in the scheme of things - I think approval was first given for its' use in 1998, if I remember right, so there are still alot of things yet to be studied with it.

You may want to consider talking to the members at the online support arm of www.thyca.org - located here:
http://health.groups.yahoo.com/group/Thyca/

And you may also find some discussions about these issues within these 2006 thyroid carcinoma treatment guidelines:
http://www.nccn.org/professionals/physician_gls/PDF/thyroid.pdf

Hope some of this helps a bit. All the best to you.

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