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New Treatment for Liver Mets

shmurciakova's picture
Posts: 910
Joined: Dec 2002

Trans-arterial chemoembolization (TACE) of liver metastases from colorectal cancer using irinotecan-eluting beads: preliminary results.

Aliberti C, Tilli M, Benea G, Fiorentini G.

Department of Interventional Radiology Delta Hospital, via delle Tombe 65, 47023 Lagosanto, Ferrara, Italy. camy.ali@libero.it

PURPOSE: The purpose of the study was to evalutate the feasibility of irinotecan drug-eluting beads (DC Bead) administered as trans-arterial chemoembolization (TACE) in patients with liver metastases from colorectal cancer (CRC). PATIENTS AND METHODS: Ten patients with liver metastases from CRC were treated with TACE adopting irinotecan-eluting beads at a dose of 100 mg every 3 weeks. Computed Tomography (CT) was performed 24h before and after TACE. RESULTS: TACE with irinotecan eluting beads was found to be feasible and well-tolerated. Right upper quadrant pain (RUQP) lasting 4 days (range 2-7) was reported by all the patients. After 30 days, a reduction >50% of CEA levels and of the lesional contrast enhancement was observed in all the patients. Conclusion: Irinotecan drug-eluting beads administered as TACE were shown to be active and safe in patients with liver metastases from CRC.

jams67's picture
Posts: 927
Joined: May 2006

Thank you for the post. All of this gives us hope. Looking forward ... jams

alta29's picture
Posts: 435
Joined: Mar 2005

I remember 2 years ago , when I started this journey...reading the cancer was going to be treated as a disease 2 years from then....maybe we are relly getting closer to it...I will have my first cea result tomorrow after I started chemo....staying really positive..will let u all know tomorow..
God bless

KathiM's picture
Posts: 8082
Joined: Aug 2005

WOW! Cool stuff! I know that we semi-colons are getting more press! And that will exchange into more possibilities of new treatments!!!

Hugs, Kathi

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