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Lupron / wild emotional variability?
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Mar 07, 2005 - 11:30 am
I started Lupron injections about a year ago. Recently (2-3 weeks ago) I began going into and out of DRASTIC depressive mood swings; never had any such volatility otherwise. No change in diagnosis, all's still going well in that regard, and I'm not prone to denial/avoidance anyhow. Given the hormonal shift, can Lupron lead to a sort of drastic semi-PMS? (I do expect to talk to my oncologist about this later this week; I'd like practical anecdotal data as well.) Thanks. |
Joined: Sep 2001
Chuck,
You are not alone in the mood swings regarding Lupron injections. I tried Lupron therapy twice with the results the same both times. After the third shot I was an emotional mess. My wife, bless her heart told me that there was not room for two women in our house. We had a good laugh about my becoming a blubbering female. I also had another side effect that may or not be the norm. My joints really started to bother me big time. I have been very active all my life and this side effect was probably the worst for me personally. It was like I had arthritis in all my joints. I am sixty and still playing softball, at least trying to play. I think they made the base paths longer when I was not looking and the fences further out.
If you can stand the mood swings and such hang in there, every time I went off my PSA elevated. The Cancer has now metastacized to my spine and several ribs. I am now waiting for my prescription of Casodex only,hopefully that will help lower the psa I also had an orchiecetmy to remove that dreaded testostornne.
Good luck, you are in my prayers
Mike Beavers Lodi, Ohio
Joined: Mar 2001
I've been on M.D. Anderson Cancer Center's version of Casodex only (aka bicalutimide monotherapy) now finishing up my 18-month prescription. Works like a hose! I currently have and had bone mets to the right shoulder, neck, spine, a few ribs, and the pelvis. I don't feel a thing...nuttin! PSA at one time was 142.2 and Casodex dropped it like a rock down to 11 (darn low for me).
Other than that, I haven't had squat...no orchiectomy, no Lupron, zip zero...nothing, period. Maybe it's my investigational nutritional supplement: Hooter's hot wings and a cold beer. Other than an American Medical Systems penile implant (ouch), my own version of adjuvant therapy includes swinging a leg over a hot Harley every chance I get.
Sometimes, treatment protocols have forks in the roads as to treatment options that are up to the patient. If soft-tissue mets don't rear their heads, the more recents stats show there's insignificant difference in survivability time-lines: bicalutimide (Casodex only) monotherapy vs total androgen blockade.
Good Luck!
Joined: Mar 2005
Good to hear of what's working. I'm keeping a journal of anecdotal support -- thanks very much for the input on Casodex.
Joined: Sep 2001
Chuck, as long as you r