Apr 28, 2004 - 2:03 pm
Hi, everyone. I am looking for some advice from people who may have already had these treatments. My 25 year old nephew has stage 2 colon cancer, had the tumor removed in an ileostomy surgery and now must undergo chemo. The doctors have presented him with the option of taking part in a research study to forego the traditional chemo. drugs used AT HIS STAGE. There are three groups which he would be randomly placed in. Group A: Oxaliplatin, 5-FU and Leucovorin (CF) (FOLFOX) Group B: Irinotecan (CPT-11), 5-FU, and CF (FOLFIRI) or Group C: Treating first with Oxaliplatin, 5-FU, and CF and then treating with Irinotecan, 5-FU and CF. It goes on to state that "the reason for the study is to find out the effectiveness of the three different combinations of drugs in preventing the return of your colon/rectal cancer (these treatments, namely Irinotecan and Oxaliplatin, are considered investigational in the stage of colon cancer that you have)" If anyone has had any of these treatments please let me know how it worked, the side effects, success, etc. It is such a hard decision for someone so young. Thanks for your reply.