Aug 04, 2003 - 11:58 pm
Richard, now 47, diagnosed May2001 after loaf-bread size tumor in stomach. UCLA hotshots left it untreated except for brief May2002 round of rutuxin withone additional experimental drug, an immune system booster oligonucleotide. No change in tumor but by July 02 he noticed increasing difficulty breathing and chalked it up to the size of the tumor(since the Docs said this was the expln). When he finally started monthly chemo in March 20 03, the tumor shrunk noticeably after 2 treatments but the breathing probs intensified and pulmonary battery of tests indicated obstructive diorder presumed to be bronchilosis obliterans. He had also suffered dry eye syndrome since Feb 03. Tissue sample of lung inconclusive, docs cease chemo until pulm probs and eyes quiet down, conclude it is overactive immune system cause (of course defer source finding), and lace him with 40mg. prednisone daily for seven weeks. No signif change in last week's repeat of pulm tests. Anyone heard of this (or similar) sequence of events? What do you think of the Prednisone regimen at this point? Dare he risk an even more invasive intrusion for a piece of tissue, esp. when it could be inconclusive again? Other thoughts welcome.