Aug 12, 2002 - 2:19 pm
I'm trying to collect information on amifostene (ethyol) use during radiation. I will be starting radiation next week, and my doctor does not want to administer the amifostene injections because "there is evidence that it may protect the cancer cells as well as the saliva glands". In doing research of my own, however, I have not found any information to this effect; rather, I have found that it is an FDA approved drug, is being tested in a multitude of clinical trials (and I have not found one stating adverse effects), and seems to be widely used for the treatment and prevention of dry mouth in radiation therapy for head and neck patients.
My question is this: what do those of you that have had radiation think of this? Has anyone else done any research on this drug? Have you found different information? If you had head/neck radiation and amifostene, what are your symptoms like? If you had radiation without amifostene, do you wish that you would have tried it? Anyone who wishes to leave their input would be greatly appreciated, as I want to feel as if I am making a sound decision on its use (or lack thereof) in my treatment.