My Dad, who just turned 60 yesterday, was diagnosed with advanced stage prostate cancer last October. His PSA was 33 and the cancer had metastisized to both hips, the lower spine, and some of his ribs. He started hormone therapy (daily pill and shot every 16 weeks), and his PSA dropped to 5.70 within 8 weeks. His pain in his right hip subsided and he began to walk w/o much of a limp! His last PSA went up to 6.75, and his pain has come back along with the limp. One doctor told him he had 1-3 years to live.....another said 3-5! Of course, we're trying to be optimistic, and shoot for the 3-5, but I'm very scared that things are starting to go downhill for him already! He just had another bone scan and x-rays and we are waiting for the results! The waiting is the hardest! I guess my question is......with this type of cancer, is it normal or common for PSA's to increase and decrease and for pain to come and go without the cancer actually getting worse? In other words, since my Dad's PSA has increased and the pain has come back, does that mean that the cancer is getting worse and spreading more? Any info would be greatly appreciated!!!! Are there any other people here who have advanced prostate cancer who would be willing to give me more info? Thank you and GOD BLESS you all!