Dec 02, 2000 - 10:47 pm
Just found this article on Femara on my e-mail provider home page. Has any one any experience with this drug or any more news on it?
Love to all
Femara is more effective than tamoxifen as a first-line treatment for breast cancer in post-menopausal women, say researchers.
It belongs to a class of products known as aromatase inhibitors, which work by blocking an enzyme needed for conversion of androgens to oestrogen, thus preventing tumour growth.
Femara, made by Novartis, which is already indicated as a second-line treatment in the disease, earlier this month won a priority review from US regulators as a first-line treatment.
"This is the first time a hormonal agent has demonstrated clear superiority to the standard treatment, tamoxifen, in one large head-to-head trial," Professor Martine Piccart, chair of the Second European Breast Cancer Conference, told the meeting in Brussels.
Femara was found to delay progression of the disease significantly, increasing the opportunity for breast-conserving surgery (lumpectomy).