poor prognosis

my wife has been treated since may of 2003 for low grade folicular nhl...three different types of chemo...including (among other things) rituxin, chop (after which there was a short remission, but the cancer returned within 4 weeks), vp16..... she had an effusion in right chest cavity which was eventually drained but continues to exist, initially a lumps under chin and under arms, eventually a painful tumor in her abdomin now the large tumor in her abdomin is as large and hard as ever..night sweats, her oncologist has indicated that he does not feel standard chmotherapy is an option, and stem cell replacement (which we were hoping to go for once in remission)is no longer an option since she is resistent to treatment..he had tests done on genetics to determine if it had genetically changed, but the cancer had not...so hse has an aggressive low grad nhl that has been resistent to therapy...doctor wants to try "zelcade"...apparently a treatment for myeloma but he believes might be useful...we are seeking a second opinion and have been told to check out phase 1 clinical trials...doctor said (when pushed to give an answer) that she probably has six months to maybe three years life expectance with maybe some years added if one of possible treatment options is helpful...pretty bleak and scary...looking for advice...we are going to university of chicago to check out options today