molecular tumor profiling

vinaykumar
vinaykumar Member Posts: 66 Member
edited October 2013 in Colorectal Cancer #1

found out that there is molecular tumor profiling avalible in india and at the hospital my dad is being treated at. however i am not sure how useful  genomic testing is. Are there folks here who have been able to action on the findings of genomic testing? finding out abt the wrong genes are right chemo is one thing but having your onc action on it is another...

Comments

  • i have the same question. i

    i have the same question. i know scubadan had a genomic (genetic? not sure what the right word is) profiling test done recently, which i remember from his earlier post is supposed to be a relatively new type of test. i've been wanting to ask him about the exact name of this test. there are others indeed who have done similar profiling tests. but my question has always been: from what i understand, these tests help determine the efficacy of certain chemo medications. but aren't there only about 5 or so types of chemo medications out there? if the number of options is limited, i am puzzled about how useful detailed genetic/genomic profiling can be? 

  • lp1964
    lp1964 Member Posts: 1,239 Member
    Dear Friends,

    As I understand it there is three types of testing.

    1. Genetic test to determine whether you have certain genes that increase the possibility of cancer in you or your relatives.

    2. Genomic testing is performed when you already have cancer and they look into your cancer's DNA to see if the cancer is a certain type. This is important because certain type of colon cancers will not react to certain chemo drugs.

    3. Chemo sensitivity test is done after a small piece of the cancer is removed. The want a small piece of the living cancer within 24 hours. They will keep these cells alive and test different chemo dugs or combination of different drugs and see how the cancer cells react. 

    I'm having the last one done or go to the Rational Therapeutics website.

     

     

  • lp1964 said:

    Dear Friends,

    As I understand it there is three types of testing.

    1. Genetic test to determine whether you have certain genes that increase the possibility of cancer in you or your relatives.

    2. Genomic testing is performed when you already have cancer and they look into your cancer's DNA to see if the cancer is a certain type. This is important because certain type of colon cancers will not react to certain chemo drugs.

    3. Chemo sensitivity test is done after a small piece of the cancer is removed. The want a small piece of the living cancer within 24 hours. They will keep these cells alive and test different chemo dugs or combination of different drugs and see how the cancer cells react. 

    I'm having the last one done or go to the Rational Therapeutics website.

     

     

    O'k, Laz, this is a good

    O'k, Laz, this is a good starting point for orientation. I will sit down and do some research now. Please keep us posted about the results of your chemo sensitivity test. 

  • lavleen
    lavleen Member Posts: 1
    chemo sensitivity test

    Does anyone know where Chemosensitivity test with patient samples are done in India?

    Lavleen

  • lp1964
    lp1964 Member Posts: 1,239 Member
    lavleen said:

    chemo sensitivity test

    Does anyone know where Chemosensitivity test with patient samples are done in India?

    Lavleen

    Dear Friend,

    I know a place here in California, but they need to get the sample in 24 hours after removal. The test is $4000. 

    Do an Internet search, maybe there are options in India as well. 

    Good luck, 

    Laz

  • DD3
    DD3 Member Posts: 136 Member
    lp1964 said:

    Dear Friend,

    I know a place here in California, but they need to get the sample in 24 hours after removal. The test is $4000. 

    Do an Internet search, maybe there are options in India as well. 

    Good luck, 

    Laz

    Testing

    We had some genetic testing done on my wife's tumor.  More concern about the possibility of "passing" something on to our kids. Which was of huge concern to her.  After seeing a geneticist and going through biology 101 again.  We were re-assured.  Nothing in he initial testing showed that she if fact passed "bad" genes onto our kids. 

    Some research folks can do on our own.  Google Lynch syndrome.  Pretty informative.